Difference between revisions of "Programmed cell death 1"
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'''Programmed cell death 1''', abbreviated '''PDCD1''' and '''PD1''',<ref name=omim600244>{{OMIM|600244}}</ref> is a protein (and gene) with an important role in immune system regulation and [[cancer]]. | '''Programmed cell death 1''', abbreviated '''PDCD1''' and '''PD1''',<ref name=omim600244>{{OMIM|600244}}</ref> is a protein (and gene) with an important role in immune system regulation and [[cancer]]. It is found on the T lymphocytes. | ||
It is also known as '''CD279'''. | It is also known as '''CD279'''. | ||
It binds with [[programmed death-ligand 1]] (dealt with separately) and ''programmed death-ligand 2''. | It binds with [[programmed death-ligand 1]] (dealt with separately) and ''programmed death-ligand 2''. | ||
Revision as of 17:16, 11 May 2016
Programmed cell death 1, abbreviated PDCD1 and PD1,[1] is a protein (and gene) with an important role in immune system regulation and cancer. It is found on the T lymphocytes.
It is also known as CD279.
It binds with programmed death-ligand 1 (dealt with separately) and programmed death-ligand 2.
Drugs
- Pembrolizumab.
- Nivolumab.
- Pidilizumab.
See also
- Programmed death-ligand 1 (PD-L1).