Post-infectious glomerulonephritis

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Post-infectious glomerulonephritis, abbreviated PIGN, is a rarely biopsied glomerulonephritis classically associated with a streptococcal infection.

General

  • Classically post-streptococcal infection.
    • Lab test: Antistreptolysin O titer (ASOT) +ve.

Microscopic

Features:

Images

www:

IF

  • Granular immune deposits.

EM

  • Subepithelial deposits - hump-like.
    • Larger when measured perpendicular to the basement membrane, if compared to membranous nephropathy.
    • Typically focal.

See also

References