Difference between revisions of "Post-infectious glomerulonephritis"
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==General== | ==General== | ||
*Classically post-streptococcal infection. | *Classically post-streptococcal infection.<ref name=pmid12746805>{{Cite journal | last1 = Barbiano Di Belgiojoso | first1 = G. | last2 = Genderini | first2 = A. | last3 = Ferrario | first3 = F. | title = [Post-infectious glomerulonephritis]. | journal = G Ital Nefrol | volume = 20 | issue = 2 | pages = 184-99 | month = | year = | doi = | PMID = 12746805 }}</ref><ref name=pmid24777751/> | ||
**Lab test: Antistreptolysin O titer (ASOT) +ve. | **Lab test: Antistreptolysin O titer (ASOT) +ve. | ||
Clinical: | |||
*[[Nephritic syndrome]].<ref name=pmid24777751>{{Cite journal | last1 = Stratta | first1 = P. | last2 = Musetti | first2 = C. | last3 = Barreca | first3 = A. | last4 = Mazzucco | first4 = G. | title = New trends of an old disease: the acute post infectious glomerulonephritis at the beginning of the new millenium. | journal = J Nephrol | volume = 27 | issue = 3 | pages = 229-39 | month = Jun | year = 2014 | doi = 10.1007/s40620-013-0018-z | PMID = 24777751 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 06:14, 11 April 2015
Post-infectious glomerulonephritis, abbreviated PIGN, is a rarely biopsied glomerulonephritis classically associated with a streptococcal infection.
General
Clinical:
Microscopic
Features:
- +/-Neutrophils - in glomerulus.
- Glomerular crescents.
Images
Post-infectious GN - high mag. (WC/Nephron)
Post-infectious GN - very high mag. (WC/Nephron)
Post-infectious GN - schematic (WC/Nephron)
www:
IF
- Granular immune deposits.
EM
- Subepithelial deposits - hump-like.
- Larger when measured perpendicular to the basement membrane, if compared to membranous nephropathy.
- Typically focal.
See also
References
- ↑ Barbiano Di Belgiojoso, G.; Genderini, A.; Ferrario, F.. "[Post-infectious glomerulonephritis].". G Ital Nefrol 20 (2): 184-99. PMID 12746805.
- ↑ 2.0 2.1 Stratta, P.; Musetti, C.; Barreca, A.; Mazzucco, G. (Jun 2014). "New trends of an old disease: the acute post infectious glomerulonephritis at the beginning of the new millenium.". J Nephrol 27 (3): 229-39. doi:10.1007/s40620-013-0018-z. PMID 24777751.