Pit1

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Pit1
Immunostain in short
Abbreviation Pit1
Normal staining pattern nuclear staining
Positive Somatotroph, lactotroph adenoma


POU domain, class 1, transcription factor 1 (growth hormone factor 1), also known as POU1F1, abbreviated Pit1, is a cimmunostain used endocrinology.

General

  • Nuclear stain.


Positive

Pit-1 lineage pituitary tumors:[1]

  • Somatotroph adenoma.
  • Lactotroph adenoma.
  • Thyreotropha adenoma.


Occasionally positive

Negative

See also

Wikipedia page: [1]

References

  1. Lloyd, RV.; Osamura, RY. (Oct 1997). "Transcription factors in normal and neoplastic pituitary tissues.". Microsc Res Tech 39 (2): 168-81. doi:10.1002/(SICI)1097-0029(19971015)39:2<168::AID-JEMT8>3.0.CO;2-H. PMID 9361268.