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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 07:34, 11 December 2015
, 07:34, 11 December 2015→Perineurioma: pic + facts
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Jensflorian (talk | contribs) (→Perineurioma: pic + facts) |
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==Perineurioma== | ==Perineurioma== | ||
===General=== | ===General=== | ||
*Benign tumour derived from perineurial cells. | *Benign tumour derived from perineurial cells (intraneural or soft tissue). | ||
**ICD-O 9571/0 | |||
** WHO grade I | |||
*Rarely malignant soft tissue perineurioma. | |||
Variant: | Variant: | ||
*Reticular perineurioma.<ref name=pmid11257623>{{Cite journal | last1 = Graadt van Roggen | first1 = JF. | last2 = McMenamin | first2 = ME. | last3 = Belchis | first3 = DA. | last4 = Nielsen | first4 = GP. | last5 = Rosenberg | first5 = AE. | last6 = Fletcher | first6 = CD. | title = Reticular perineurioma: a distinctive variant of soft tissue perineurioma. | journal = Am J Surg Pathol | volume = 25 | issue = 4 | pages = 485-93 | month = Apr | year = 2001 | doi = | PMID = 11257623 }}</ref> | *Reticular perineurioma.<ref name=pmid11257623>{{Cite journal | last1 = Graadt van Roggen | first1 = JF. | last2 = McMenamin | first2 = ME. | last3 = Belchis | first3 = DA. | last4 = Nielsen | first4 = GP. | last5 = Rosenberg | first5 = AE. | last6 = Fletcher | first6 = CD. | title = Reticular perineurioma: a distinctive variant of soft tissue perineurioma. | journal = Am J Surg Pathol | volume = 25 | issue = 4 | pages = 485-93 | month = Apr | year = 2001 | doi = | PMID = 11257623 }}</ref> | ||
===Macroscopy=== | |||
*Intraneural perineurioma: segmental tubular enlargement of the nerve. | |||
*Soft tissue perineurioma: Well circumscribed, but not encapsulated. | |||
===Microscopic=== | ===Microscopic=== | ||
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Note: | Note: | ||
*May be intraneural.<ref name=Ref_Sternberg5_424>{{Ref Sternberg5|424}}</ref> | *May be intraneural.<ref name=Ref_Sternberg5_424>{{Ref Sternberg5|424}}</ref> | ||
**Typical pseudo-onion bulbs. | |||
**Long considered hypertrophic neuropathy. | |||
**Rare (less than 1% of all nerve sheath tumours). | |||
DDx: | DDx: | ||
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Images: | Images: | ||
*[http://www.conganat.org/seap/reuniones/almagro2000/scruz/tnerviog5.htm | *[http://www.conganat.org/seap/reuniones/almagro2000/scruz/tnerviog5.htm Perineurioma (conganat.org)]. | ||
<gallery> | |||
File:Perineurioma,_HE_stain.jpg | Pseudo-onion bulbs in a intraneural perioneurioma (WC/jensflorian) | |||
</gallery> | |||
===IHC=== | ===IHC=== | ||