Penis

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The penis is occasionally afflicted by disease that the pathologist see.

It is afflicted by common skin pathologies.

Diseases

Inflammatory

Infectious

Other non-tumour

Pre-cancerous

Neoplastic

Others:

Specific conditions

Phimosis

General

  • Cannot be retract foreskin.
  • This is a clinical diagnosis.

Microscopic

Features:[1]

  • +/-Inflammation.
  • Fibrosis.

Notes: Findings non-specific.

DDx - general:

Penile fibromatosis

  • AKA Peyronie's disease.

General

  • Prevalence ~5%.[2]

Treatment:

  • Conservative versus surgery.

Gross

  • Abnormal curvature of the penis, esp. in the erect state.

Microscopic

Features:[2]

  • Tunica albuginea fibrosis.

Zoon balanitis

  • AKA balanitis circumscripta plasmacellularis.[3]
  • AKA plasma cell balanitis.[4]

General

  • Balanitis = inflammation of glands penis.
  • Rare.
  • Uncircumsized men.

Microscopic

Features:[3]

DDx:

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PENILE FORESKIN, CIRCUMCISION:
- COMPATIBLE WITH PLASMA CELL BALANITIS (ZOON BALANITIS), SEE COMMENT.

COMMENT:
A treponemal infection should be considered clinically.

Micro

The section show a stratified squamous epithelium with spongiosis, intraepithelial lymphocytes, moderate acanthosis and focal parakeratosis. The dermis shows abundant plasma cells, superficial fibrosis, lymphocytes and prominent superficial blood vessels.

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 391. ISBN 978-0781765275.
  2. 2.0 2.1 Serefoglu, EC.; Hellstrom, WJ. (Dec 2011). "Treatment of Peyronie's disease: 2012 update.". Curr Urol Rep 12 (6): 444-52. doi:10.1007/s11934-011-0212-2. PMID 21818660.
  3. 3.0 3.1 Balato, N.; Scalvenzi, M.; La Bella, S.; Di Costanzo, L. (2009). "Zoon's Balanitis: Benign or Premalignant Lesion?". Case Rep Dermatol 1 (1): 7-10. doi:10.1159/000210440. PMID 20652106.
  4. Korenaga, D.; Kanematsu, T.; Watanabe, A.; Maehara, Y.; Kitano, S.; Sugimachi, K. (Feb 1991). "Clinical management of gastric cancer and concomitant esophagogastric varices.". J Surg Oncol 46 (2): 91-6. PMID 1992223.