Difference between revisions of "Pancreas"

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=Cystic lesions=
=Cystic lesions=
==Serous cystic tumours==
==Serous tumours - overview==
===General===
===General===
*Cell of origin: intralobular duct cells (ductular cells).
*Cell of origin: intralobular duct cells (ductular cells).
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====Subclassication====
====Subclassication====
*Serous microcystic adenoma ([[AKA]] serous cystadenoma<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref>).
*[[Serous microcystic adenoma]] ([[AKA]] serous cystadenoma<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref>).
** Many small cysts.
** Many small cysts.
*Serous oligocystic adenoma.
*Serous oligocystic adenoma.
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*If one mucin +ve cell, tumour = a mucinous tumour.
*If one mucin +ve cell, tumour = a mucinous tumour.


=====Characteristics of serous microcystic adenoma=====
==Serous cystadenoma of the pancreas==
*1-2% of all exocrine pancratic tumours.
*[[AKA]] ''serous microcystic adenoma''.<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref>
===General===
*1-2% of all exocrine pancreatic tumours.
*Female > male.
*Female > male.
*Mean age 66 years.
*Mean age 66 years.
*Truly benign with no malignant potenial.
*Truly benign with no malignant potenial.
*May not require surgical resection.
*May be part of [[von Hippel-Lindau syndrome]].
*May be part of [[von Hippel-Lindau syndrome]].
*50-70% occur in the body and tail.
*Average size 11 cm.


===Radiology===
Management:
*Honey comb appearance.
*Observe or resect.
*"Coin lesion" - well demarcated border.
*May have characteristic central scar.<ref name=pmid15888617>{{cite journal |author=Kim YH, Saini S, Sahani D, Hahn PF, Mueller PR, Auh YH |title=Imaging diagnosis of cystic pancreatic lesions: pseudocyst versus nonpseudocyst |journal=Radiographics |volume=25 |issue=3 |pages=671–85 |year=2005 |pmid=15888617 |doi=10.1148/rg.253045104 |url=http://radiographics.rsna.org/content/25/3/671.abstract}}</ref>


===Gross===
===Gross===
Features:
*Classically has a characteristic central scar.<ref name=pmid15888617>{{cite journal |author=Kim YH, Saini S, Sahani D, Hahn PF, Mueller PR, Auh YH |title=Imaging diagnosis of cystic pancreatic lesions: pseudocyst versus nonpseudocyst |journal=Radiographics |volume=25 |issue=3 |pages=671–85 |year=2005 |pmid=15888617 |doi=10.1148/rg.253045104 |url=http://radiographics.rsna.org/content/25/3/671.abstract}}</ref>
*Bosulated surface.
*Bosulated surface.
**Lobulated.
*Lobulated.
*No (macroscopic) cysts apparent on gross.
*No (macroscopic) cysts apparent on gross.
*Location: 50-70% occur in the body and tail.
*Size: average size 11 cm.
Radiologic appearance:
*Honey comb-like appearance.
*Well demarcated border - may be described as a "coin lesion".


Image:
Image:
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DDx:
DDx:
*[[Renal cell carcinoma]].
*[[Renal cell carcinoma]].
*[[Lympangioma]].
*[[Lymphangioma]].
*[[Hemangioma]].
*[[Hemangioma]].
*Oligocystic mucinous cystic tumors and pseudocysts.
*Oligocystic mucinous cystic tumors and pseudocysts.
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