Difference between revisions of "Other CNS embryonal tumours"

Line 35:

==General==

Other CNS embryonal tumours are a group of primitive neuroeptithelial tumors that are to be classified in distinct molecular groups in the future.

Currently it is a exlcusion criteria encompassing four subgroups

Currently it is a exlcusion criteria encompassing four morphological subgroups

*CNS neuroblastomas

*CNS ganglioneuroblastomas.

Line 42:

** but absence of C19MC alteration, otherwise classified as [[ETMR]]

* CNS embryonal tumour, NOS

** Currently four distinct subtypes can be discriminated by molecular analysis.<ref>{{cite journal |vauthors=Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DTW, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, Reimand J, Mackay A, Carvalho DM, Remke M, Phillips JJ, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Łastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley BC, Schniederjan MJ, Santi M, Buccoliero AM, Dahiya S, Kramm CM, von Bueren AO, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald MC, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins VP, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann MU, Shalaby T, Grotzer M, van Meter T, Monoranu CM, Felsberg J, Reifenberger G, Snuderl M, Forrester LA, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore AS, Taylor MD, Jones C, Jabado N, Karajannis MA, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister SM, Ellison DW, Korshunov A, Kool M |title=New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs |journal=Cell |volume=164 |issue=5 |pages=1060–1072 |date=February 2016 |pmid=26919435 |pmc=5139621 |doi=10.1016/j.cell.2016.01.015 |url=}}</ref>

** Similarities to astroblastoma: ''High‐grade neuroepithelial tumours with MN1 alteration (HGNET‐MN1)''

** NUTM1-positive IHC: ''Ewing's sarcoma family tumour with CIC alteration (EFT‐CIC)''

Difference between revisions of "Other CNS embryonal tumours"

Navigation menu

Search

@@ Line 35: / Line 35: @@
 ==General==
 Other CNS embryonal tumours are a group of primitive neuroeptithelial tumors that are to be classified in distinct molecular groups in the future.
-Currently it is a exlcusion criteria encompassing four subgroups
+Currently it is a exlcusion criteria encompassing four morphological subgroups
 *CNS neuroblastomas
 *CNS ganglioneuroblastomas.
@@ Line 42: / Line 42: @@
 ** but absence of C19MC alteration, otherwise classified as [[ETMR]]
 * CNS embryonal tumour, NOS
+** Currently four distinct subtypes can be discriminated by molecular analysis.<ref>{{cite journal |vauthors=Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DTW, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, Reimand J, Mackay A, Carvalho DM, Remke M, Phillips JJ, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Łastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley BC, Schniederjan MJ, Santi M, Buccoliero AM, Dahiya S, Kramm CM, von Bueren AO, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald MC, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins VP, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann MU, Shalaby T, Grotzer M, van Meter T, Monoranu CM, Felsberg J, Reifenberger G, Snuderl M, Forrester LA, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore AS, Taylor MD, Jones C, Jabado N, Karajannis MA, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister SM, Ellison DW, Korshunov A, Kool M |title=New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs |journal=Cell |volume=164 |issue=5 |pages=1060–1072 |date=February 2016 |pmid=26919435 |pmc=5139621 |doi=10.1016/j.cell.2016.01.015 |url=}}</ref>
 ** Similarities to astroblastoma: ''High‐grade neuroepithelial tumours with MN1 alteration (HGNET‐MN1)''
 ** NUTM1-positive IHC:  ''Ewing's sarcoma family tumour with CIC alteration (EFT‐CIC)''