Oncogene
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An oncogene is a cancer gene, derived from a proto-oncogene.
Examples
Gene | Cancer |
---|---|
EGFR[1] | lung adenocarcinoma, glioblastoma,[2] anaplastic astrocytoma[2] |
PDGFB[3] | dermatofibrosarcoma protuberans |
BRAF[4] | papillary thyroid carcinoma tall cell variant |
KRAS[5] | invasive ductal carcinoma of the pancreas |
MYC[6] | Burkitt lymphoma |
MET[7] | papillary renal cell carcinoma |
ERBB2 (HER2)[8] | invasive breast carcinoma |
CCND1 (BCL1)[9] | mantle cell lymphoma |
EWSR1[10] | Ewing sarcoma, clear cell sarcoma, DSRCT, EMC |
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 131550
- ↑ 2.0 2.1 Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 419 Q6. ISBN 978-1416025887.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190040
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164757
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190070
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190080
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164860
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164870
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 168461
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 133450