Difference between revisions of "Oncogene"

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'''Oncogene''' is a cancer gene.   
An '''oncogene''' is a [[cancer]] gene, derived from a '''proto-oncogene'''.   


Examples:
==Examples==
*EGFR<ref name=omim131550>{{OMIM|131550}}</ref> - [[lung adenocarcinoma]].
{| class="wikitable sortable"
*PDGFB<ref name=omim190040>{{OMIM|190040}}</ref> - [[dermatofibrosarcoma protuberans]].
! Gene
*BRAF.<ref name=omim164757>{{OMIM|164757}}</ref>
! Cancer
*KRAS.<ref name=omim190070>{{OMIM|190070}}</ref>
|-
*MYC<ref name=omim190080>{{OMIM|190080}}</ref> - [[Burkitt lymphoma]].
| EGFR<ref name=omim131550>{{OMIM|131550}}</ref>  
| [[lung adenocarcinoma]], [[glioblastoma]],<ref name=Ref_APBR419>{{Ref APBR|419 Q6}}</ref> [[anaplastic astrocytoma]]<ref name=Ref_APBR419>{{Ref APBR|419 Q6}}</ref>
|-
| PDGFB<ref name=omim190040>{{OMIM|190040}}</ref>  
| [[dermatofibrosarcoma protuberans]]
|-
| BRAF<ref name=omim164757>{{OMIM|164757}}</ref>  
| [[papillary thyroid carcinoma tall cell variant]]
|-
| [[KRAS mutation|KRAS]]<ref name=omim190070>{{OMIM|190070}}</ref>  
| [[invasive ductal carcinoma of the pancreas]]
|-
| MYC<ref name=omim190080>{{OMIM|190080}}</ref>  
| [[Burkitt lymphoma]]
|-
| MET<ref name=omim164860>{{OMIM|164860}}</ref>
| [[papillary renal cell carcinoma]]
|-
| ERBB2 (HER2)<ref name=omim164870>{{OMIM|164870}}</ref>
| [[invasive breast carcinoma]]
|-
| CCND1 (BCL1)<ref name=omim168461>{{OMIM|168461}}</ref>
| [[mantle cell lymphoma]]
|-
| EWSR1<ref name=omim133450>{{OMIM|133450}}</ref>
| [[Ewing sarcoma]], [[clear cell sarcoma]], [[DSRCT]], [[extraskeletal myxoid chondrosarcoma|EMC]]
|}


==See also==
==See also==

Latest revision as of 12:07, 30 April 2014