Difference between pages "Autoimmune metaplastic atrophic gastritis" and "Chronic sialadenitis"
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'''Chronic sialadenitis''' is a chronic inflammatory process involving a [[salivary glands|salivary gland]]. | |||
'''Chronic sailolithiasis''' redirects here. | |||
'''Sialadenitis''' redirects here. | |||
| | |||
''' | |||
==General== | ==General== | ||
* | *Occasionally associated with malignancy, e.g. [[adenoid cystic carcinoma]].<ref name=pmid21159490>{{cite journal |author=Hasegawa M, Cheng J, Maruyama S, ''et al.'' |title=Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background |journal=Int J Oral Maxillofac Surg |volume=40 |issue=6 |pages=647–50 |year=2011 |month=June |pmid=21159490 |doi=10.1016/j.ijom.2010.11.009 |url=}}</ref> | ||
Etiology:<ref>URL: [http://emedicine.medscape.com/article/882358-overview http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview]. Accessed on: 10 January 2011.</ref> | |||
* | *Infection. | ||
* | *Autoimmune (e.g. [[Sjögren syndrome]], [[systemic lupus erythematosus]]). | ||
*Other. | |||
Associations: | |||
* | *[[Smoking]].<ref name=pmid2037973>{{cite journal |author=Eliasson L, Heyden G, Landahl S, Steen B |title=Effects of tobacco and diuretics on human palatal salivary glands |journal=J. Oral Pathol. Med. |volume=20 |issue=3 |pages=126–9 |year=1991 |month=March |pmid=2037973 |doi= |url=}}</ref> (???) | ||
==Gross== | ==Gross== | ||
* | Features: | ||
*Typical location: submandibular salivary gland. | |||
*Salivary gland swelling.<ref name=pmid21159490/> | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
* | *Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, [[plasma cell]]s). | ||
* | *Fibrosis. | ||
* | *+/-Calcifications. | ||
Note: | |||
* | *If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a ''[[Focus score]]'' should be considered. | ||
DDx: | DDx: | ||
*[[ | *[[Lymphoma]] - especially [[MALT lymphoma]].<ref name=pmid22475637>{{Cite journal | last1 = Beasley | first1 = MJ. | title = Lymphoma of the Thyroid and Head and Neck. | journal = Clin Oncol (R Coll Radiol) | volume = | issue = | pages = | month = Apr | year = 2012 | doi = 10.1016/j.clon.2012.02.010 | PMID = 22475637 }}</ref> | ||
*[[ | *[[IgG4-related systemic diseases|IgG4-related sialadenitis]].<ref name=pmid31760789>{{cite journal |authors=Thompson LDR |title=IgG4-Related Sialadenitis |journal=Ear Nose Throat J |volume= |issue= |pages=145561319890153 |date=November 2019 |pmid=31760789 |doi=10.1177/0145561319890153 |url=}}</ref> | ||
=== | ===Image=== | ||
<gallery> | <gallery> | ||
Image: | Image:Chronic_sialadenitis.jpg | Chronic sialadenitis. (WC/Nephron) | ||
</gallery> | </gallery> | ||
==Sign out== | ==Sign out== | ||
<pre> | <pre> | ||
SUBMANDIBULAR GLAND, RIGHT, EXCISION: | |||
- | - CHRONIC SIALOADENITIS. | ||
- | - SIALOLITHIASIS. | ||
- | - TWO BENIGN LYMPH NODES. | ||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
====Micro==== | |||
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell | |||
infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. | |||
Significant nuclear atypia is not identified. | |||
=====Alternate===== | |||
is | The sections show a salivary gland with a patchy mixed mononuclear cell infiltrate and fibrosis. Significant nuclear atypia is not identified. Plasma cells are not prominent. Germinal centres are present. | ||
==See also== | ==See also== | ||
*[[ | *[[Salivary gland]]. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Salivary gland]] |
Revision as of 20:28, 24 May 2020
Chronic sialadenitis is a chronic inflammatory process involving a salivary gland.
Chronic sailolithiasis redirects here. Sialadenitis redirects here.
General
- Occasionally associated with malignancy, e.g. adenoid cystic carcinoma.[1]
Etiology:[2]
- Infection.
- Autoimmune (e.g. Sjögren syndrome, systemic lupus erythematosus).
- Other.
Associations:
Gross
Features:
- Typical location: submandibular salivary gland.
- Salivary gland swelling.[1]
Microscopic
Features:
- Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, plasma cells).
- Fibrosis.
- +/-Calcifications.
Note:
- If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a Focus score should be considered.
DDx:
- Lymphoma - especially MALT lymphoma.[4]
- IgG4-related sialadenitis.[5]
Image
Sign out
SUBMANDIBULAR GLAND, RIGHT, EXCISION: - CHRONIC SIALOADENITIS. - SIALOLITHIASIS. - TWO BENIGN LYMPH NODES. - NEGATIVE FOR MALIGNANCY.
Micro
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. Significant nuclear atypia is not identified.
Alternate
The sections show a salivary gland with a patchy mixed mononuclear cell infiltrate and fibrosis. Significant nuclear atypia is not identified. Plasma cells are not prominent. Germinal centres are present.
See also
References
- ↑ 1.0 1.1 Hasegawa M, Cheng J, Maruyama S, et al. (June 2011). "Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background". Int J Oral Maxillofac Surg 40 (6): 647–50. doi:10.1016/j.ijom.2010.11.009. PMID 21159490.
- ↑ URL: http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview. Accessed on: 10 January 2011.
- ↑ Eliasson L, Heyden G, Landahl S, Steen B (March 1991). "Effects of tobacco and diuretics on human palatal salivary glands". J. Oral Pathol. Med. 20 (3): 126–9. PMID 2037973.
- ↑ Beasley, MJ. (Apr 2012). "Lymphoma of the Thyroid and Head and Neck.". Clin Oncol (R Coll Radiol). doi:10.1016/j.clon.2012.02.010. PMID 22475637.
- ↑ Thompson LDR (November 2019). "IgG4-Related Sialadenitis". Ear Nose Throat J: 145561319890153. doi:10.1177/0145561319890153. PMID 31760789.