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Difference between revisions of "Nuclear atypia"
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[[Image:Colorectal adenocarcinoma - alt -- high mag.jpg|thumb|right|200px|Nuclear atypia and [[stromal desmoplasia]] in [[colorectal adenocarcinoma]]. [[H&E stain]].]] | [[Image:Colorectal adenocarcinoma - alt -- high mag.jpg|thumb|right|200px|Nuclear atypia and [[stromal desmoplasia]] in a [[colorectal adenocarcinoma]]. [[H&E stain]].]] | ||
'''Nuclear atypia''', also '''atypical nuclei''', is an abnormal change of the cell nucleus. | '''Nuclear atypia''', also '''atypical nuclei''', is an abnormal change of the cell nucleus. | ||
Nuclear atypia is often seen in [[malignancy]]; however, it may be seen in benign conditions - notably inflammation. | Nuclear atypia is often seen in [[malignancy]]; however, it may be seen in benign conditions - notably inflammation. Also, nuclear atypia in endocrine organs (known as ''[[endocrine atypia]]'') is considered normal. | ||
==Cancer with no appreciable or minimal nuclear atypia== | ==Cancer with no appreciable or minimal nuclear atypia== | ||
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*[[Nuclear pleomorphism]]. | *[[Nuclear pleomorphism]]. | ||
*[[Reactive atypia]]. | *[[Reactive atypia]]. | ||
*[[Vesicular nuclei]]. | |||
*[[Endocrine atypia]]. | |||
[[Category:Basics]] | [[Category:Basics]] | ||