Difference between revisions of "Non-malignant skin disease"

Non-malignant skin disease (view source)

833 bytes added , 02:38, 21 August 2010

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 ==Lichen simplex chronicus==
-===Histology===
+===General===
-Key features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref>
+*Variant of ''spongiotic dermatitis''.<ref name=Ref_DCHH296>{{Ref DCHH|296}}</ref>
+Etiology:<ref>URL: [http://emedicine.medscape.com/article/1123423-overview http://emedicine.medscape.com/article/1123423-overview]. Accessed on: 20 August 2010.</ref>
+*Pruritus -> mechanical trauma -> lichenification (thickened/leathery<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=10131 http://www.medterms.com/script/main/art.asp?articlekey=10131]. Accessed on: 20 August 2010.</ref>.
+===Microscopic===
+Features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref>
 *Acanthosis (epithelial thickening).
 *Hyperkeratosis.
+Other features:<ref>URL: [http://emedicine.medscape.com/article/1123423-diagnosis http://emedicine.medscape.com/article/1123423-diagnosis]. Accessed on: 20 August 2010.</ref>
+*Spongiosis (epidermal intercellular edema -- cells appear to have a clear halo around 'em).
+*Parakeratosis = retention of nuclei in the stratum corneum.
 ==Seborrheic keratosis==