Difference between revisions of "Neuropathology"

Neuropathology (view source)

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 *Abbreviated ''CVA''.
 *[[AKA]] ''stroke''.
+{{Main|Cerebrovascular accident}}
-===General===
-*Very common.
-*Leading cause of morbidity and mortality.
-Clinical classification:
-# Hemorrhagic stroke.
-# Ischemic stroke.
-===Gross===
-*Soft/mushy brain.
-*Older [[infarct]]s.
-**A "roof" is present - a thin submeningeal layer is preserved by the CSF.<ref>MUN. 16 December 2009.</ref>
-***"Roof" is absent in trauma.
-**Cavity - in older infarcts.
-***''[[Multiple sclerosis]]'' does not cavitate.
-*Laminar necrosis = (thin) chalky line replaces grey mater.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm]. Accessed on: 26 October 2010.</ref>
-**[[AKA]] ''pseudolaminar necrosis'' - as it is not localized to a specific layer of the cortex.<ref>MUN. 26 November 2010.</ref>
-DDx:
-*[[Cerebral contusion]].
-===Microscopic===
-Features:
-*Ischemic neurons.
-*+/-Neuronal loss.
-*+/-Microglial.
-*+/-[[Thrombosis]].
-*+/-[[Atherosclerosis]].
 ==Hypoxic-ischemic encephalopathy==