Difference between revisions of "Neurocytoma"

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Line 10: Line 10:
*Perinuclear clearing.
*Perinuclear clearing.
*Well-defined cell borders.
*Well-defined cell borders.
==IHC==
*MIB-1: Usu. low.
*Synapthophysin +ve.


DDx:
DDx:
Line 15: Line 20:
*[[Ganglioglioma]].
*[[Ganglioglioma]].
*[[Ependymoma]].
*[[Ependymoma]].
*[[Pilocytic astrocytoma]] (with predominantly oligo-like cell component).
* Diffuse leptomeningeal gliomeuronal tumour.


===Images===
===Images===

Revision as of 11:59, 9 July 2018

Neurocytoma is a rare neuropathology tumour.

General

  • Rare.

Microscopic

Features:[1]

  • Pineocytomatous/neurocytic rosette = irregular rosette with a large meshwork of fibers (neuropil) at the centre.[2]
    • Similar to Homer-Wright rosette.
  • Perinuclear clearing.
  • Well-defined cell borders.

IHC

  • MIB-1: Usu. low.
  • Synapthophysin +ve.


DDx:


Images

www:

IHC

  • Synaptophysin +ve.
    • Most glial tumour -ve.[3]

See also

References

  1. URL: http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm. Accessed on: 12 October 2011.
  2. Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
  3. URL: http://path.upmc.edu/cases/case383/dx.html. Accessed on: 15 January 2012.