Difference between revisions of "Micropapillary urothelial carcinoma"

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*EMA +ve.<ref name=pmid25673582/>
*EMA +ve.<ref name=pmid25673582/>
*HER2 +ve/-ve.<ref name=pmid25673582/>
*HER2 +ve/-ve.<ref name=pmid25673582/>
*p63 -ve/+ve.<ref name=pmid24993315>{{Cite journal  | last1 = Lin | first1 = X. | last2 = Zhu | first2 = B. | last3 = Villa | first3 = C. | last4 = Zhong | first4 = M. | last5 = Kundu | first5 = S. | last6 = Rohan | first6 = SM. | last7 = Yang | first7 = XJ. | title = The utility of p63, p40, and GATA-binding protein 3 immunohistochemistry in diagnosing micropapillary urothelial carcinoma. | journal = Hum Pathol | volume = 45 | issue = 9 | pages = 1824-9 | month = Sep | year = 2014 | doi = 10.1016/j.humpath.2014.04.015 | PMID = 24993315 }}</ref>
*p40 -ve/+ve.<ref name=pmid24993315/>
*GATA3 +ve.<ref name=pmid24993315/>
*GATA3 +ve.<ref name=pmid24993315/>
Others:<ref name=pmid24993315>{{Cite journal  | last1 = Lin | first1 = X. | last2 = Zhu | first2 = B. | last3 = Villa | first3 = C. | last4 = Zhong | first4 = M. | last5 = Kundu | first5 = S. | last6 = Rohan | first6 = SM. | last7 = Yang | first7 = XJ. | title = The utility of p63, p40, and GATA-binding protein 3 immunohistochemistry in diagnosing micropapillary urothelial carcinoma. | journal = Hum Pathol | volume = 45 | issue = 9 | pages = 1824-9 | month = Sep | year = 2014 | doi = 10.1016/j.humpath.2014.04.015 | PMID = 24993315 }}</ref>
*p63 -ve/+ve.
*p40 -ve/+ve.


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Revision as of 09:20, 15 June 2015

Micropapillary urothelial carcinoma is an aggressive variant of urothelial carcinoma.[1]

General

Microscopic

Features:[1]

  • Micropapillae.
    • Quantity of micropapillary (percentage) is variable.[2]
  • Conventional urothelial carcinoma (typical).

DDx:

  • Metastasis (breast, ovary, lung, pancreas, salivary gland).

Images

Case

www

IHC

Features:

Others:[3]

  • p63 -ve/+ve.
  • p40 -ve/+ve.

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See also

References

  1. 1.0 1.1 1.2 Compérat, E.; Roupret, M.; Yaxley, J.; Reynolds, J.; Varinot, J.; Ouzaïd, I.; Cussenot, O.; Samaratunga, H. (Dec 2010). "Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 cases.". Pathology 42 (7): 650-4. doi:10.3109/00313025.2010.522173. PMID 21080874.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Chatterjee, D.; Das, A.; Radotra, BD.. "Invasive micropapillary carcinoma of urinary bladder: a clinicopathological study.". Indian J Pathol Microbiol 58 (1): 2-6. doi:10.4103/0377-4929.151153. PMID 25673582.
  3. 3.0 3.1 Lin, X.; Zhu, B.; Villa, C.; Zhong, M.; Kundu, S.; Rohan, SM.; Yang, XJ. (Sep 2014). "The utility of p63, p40, and GATA-binding protein 3 immunohistochemistry in diagnosing micropapillary urothelial carcinoma.". Hum Pathol 45 (9): 1824-9. doi:10.1016/j.humpath.2014.04.015. PMID 24993315.