Difference between revisions of "Medical kidney diseases"

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*Lupus.
*Lupus.


===Bland necrotic crescents===
===Crescents===
*Indicate a rapidly progressive disease.
*Etiology/definition: break in the glomerular basement membrane (GBM).
 
Microscopic:
*Break in the glomerular basement membrane - '''key feature'''.
**Best seen on a silver stain (e.g. [[Jones stain]]).
*Fibrin.
**Described as orange on [[HPS stain|HPS]].
*Cellular debris.
*Inflammatory cells (lymphocytes, plasma cells, eosinophils, macrophages).
 
====Bland necrotic crescents====
DDx:
DDx:
*ANCA-related glomerulonephritis.
*ANCA-related glomerulonephritis.
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