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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 05:09, 10 November 2010
, 05:09, 10 November 2010tweaking here and there
(tweaking here and there) |
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==Basic approach to renal biopsy== | ==Basic approach to renal biopsy== | ||
===Basic components=== | |||
*Glomeruli. | *Glomeruli. | ||
*Tubules. | *Tubules. | ||
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===Vessels=== | ===Vessels=== | ||
#Arteriolar hyalinosis - too much pink stuff | #Arteriolar hyalinosis - too much pink stuff? | ||
#Intimal hyperplasia. | #Intimal hyperplasia. | ||
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===Arteriolar hyalinosis=== | ===Arteriolar hyalinosis=== | ||
Microscopic: | |||
*Pink acellular crap replaces arteriolar wall. | |||
DDx: | DDx: | ||
*Diabetes mellitus. | *Diabetes mellitus. | ||
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*Aging. | *Aging. | ||
*Drugs - tarolimus, cyclosporine. | *Drugs - tarolimus, cyclosporine. | ||
Note: | Note: | ||
*Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only tha afferent. | *Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only tha afferent. | ||
===Mesangial hypercellularity=== | ===Mesangial hypercellularity=== | ||
DDx: | |||
# Lupus. | # Lupus (SLE). | ||
# IgA nephropathy. | # IgA nephropathy. | ||
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*Membranoproliferative glomerulonephritis (MPGN). | *Membranoproliferative glomerulonephritis (MPGN). | ||
<!-- NOT COMPLETE | |||
===Patterns - Table=== | ===Patterns - Table=== | ||
{| class="wikitable" | {| class="wikitable" | ||
| Line 266: | Line 268: | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|- | |||
| Pattern | | Pattern | ||
| Key feature? | | Key feature? | ||
| Line 273: | Line 275: | ||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|} | |} | ||
--> | |||
==Nephrotic syndrome== | ==Nephrotic syndrome== | ||
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*Abbreviated ''LN''. | *Abbreviated ''LN''. | ||
*Bread & butter of nephropathology. | *Bread & butter of nephropathology. | ||
===Immunofluorescence=== | |||
*"Full house" = call of 'em light up. | |||
===Classification=== | ===Classification=== | ||