Difference between revisions of "Lymph node pathology"

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===Microscopic===
===Microscopic===
Features:<ref name=ILNP226>{{Ref ILNP|226}}</ref>
Features:<ref name=ILNP226>{{Ref ILNP|226}}</ref>
*Abundant histiocytes & "special" cells - '''key feature''':
*Abundant histiocytes & special histiocytes - in loose irregular clusters '''key feature''':
**Histiocytes +/- melanin pigment '''key feature''' if present.
**Do ''not'' form granuloma; may be similar to ''toxoplasma''.
**Interdigitating dendritic cells.
*Plasma cells (medulla).
**Langerhans cells.
*Eosinophils.
*+/-Plasma cells.
 
*+/-Eosinophils.
Histiocytes & special histiocytes:
*Histiocytes:
**+/-Melanin pigment '''key feature''' (if present).
**Lipid-laden macrophages.
*Interdigitating dendritic cells:
**Need IHC to identify definitively.
*Langerhans cells:
**Classically have a kidney bean nuclei.
**Need IHC to identify definitively.


IHC:
IHC:
48,460

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