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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=ILNP226>{{Ref ILNP|226}}</ref> | Features:<ref name=ILNP226>{{Ref ILNP|226}}</ref> | ||
*Abundant histiocytes & | *Abundant histiocytes & special histiocytes - in loose irregular clusters '''key feature''': | ||
**Histiocytes +/- | **Do ''not'' form granuloma; may be similar to ''toxoplasma''. | ||
**Interdigitating dendritic cells. | *Plasma cells (medulla). | ||
*Eosinophils. | |||
* | |||
* | Histiocytes & special histiocytes: | ||
*Histiocytes: | |||
**+/-Melanin pigment '''key feature''' (if present). | |||
**Lipid-laden macrophages. | |||
*Interdigitating dendritic cells: | |||
**Need IHC to identify definitively. | |||
*Langerhans cells: | |||
**Classically have a kidney bean nuclei. | |||
**Need IHC to identify definitively. | |||
IHC: | IHC: |
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