Lung bleb

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Lung blebs, also pulmonary belbs, are benign cystic lung lesions.[1]

General

Clinical history:

Gross

Cystic lesions:[2]

  • Bleb <=1 cm.
  • Bulla >1 cm, wall-thickness <= 1 mm.

Microscopic

Features:

  • Thin-wall cystic lesions.
    • Blebs are entirely intrapleural.[3]

DDx:

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BLEBS, APEX OF THE LEFT LUNG, WEDGE RESECTION:
- BENIGN LUNG BLEBS.
- EVIDENCE OF PULMONARY HEMORRHAGE.
- NEGATIVE FOR MALIGNANCY.

Micro

The sections show peripheral lung with large dilated air spaces surrounded by a thin walls and lined by respiratory-type epithelium. Siderophages are focally increased. Focal fibrous pleural thickening is present. No significant inflammation is present.

The airspaces and lung interstitium distant from the abnormality is unremarkable. There is no interstitial fibrosis.

References

  1. Ryu, JH.; Swensen, SJ. (Jun 2003). "Cystic and cavitary lung diseases: focal and diffuse.". Mayo Clin Proc 78 (6): 744-52. doi:10.4065/78.6.744. PMID 12934786.
  2. Hansell, DM.; Bankier, AA.; MacMahon, H.; McLoud, TC.; Müller, NL.; Remy, J. (Mar 2008). "Fleischner Society: glossary of terms for thoracic imaging.". Radiology 246 (3): 697-722. doi:10.1148/radiol.2462070712. PMID 18195376.
  3. Leslie, Kevin O.; Wick, Mark R. (2004). Practical Pulmonary Pathology: A Diagnostic Approach (1st ed.). Churchill Livingstone. pp. 787. ISBN 978-0443066313.