Intramuscular myxoma

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Intramuscular myxoma
Diagnosis in short

Intramuscular myxoma.

LM myxoid stroma with bland stellate cells and/or bland spindle cells, intramuscular, usu. hypervascular and hypercellular
Subtypes hypercellular, hypervascular
LM DDx myxoid lesions
Site Soft tissue

Intramuscular myxoma is an uncommon benign intramuscular myxoid lesion.

General

  • Rare.[1]
  • Usually do not recur.[2]
  • Present as a mass.[2]

Gross

  • Usually thigh muscles.[2]

Microscopic

Features:[1][3]

  • Myxoid stroma - key feature
  • Bland stellate or spindle cells.
    • Typically paucicellular. †
    • Usually with scant vascularity. ‡
  • Contained within skeletal muscle - essential.

Note:

  • † A hypercellular variant exists.
  • ‡ A hypervascular variant exists.

DDx:[3]

Images

See also

References

  1. 1.0 1.1 Charron, P.; Smith, J. (Dec 2004). "Intramuscular myxomas: a clinicopathologic study with emphasis on surgical management.". Am Surg 70 (12): 1073-7. PMID 15663047.
  2. 2.0 2.1 2.2 Silver, WP.; Harrelson, JM.; Scully, SP. (Oct 2002). "Intramuscular myxoma: a clinicopathologic study of 17 patients.". Clin Orthop Relat Res (403): 191-7. PMID 12360026.
  3. 3.0 3.1 Nielsen, GP.; O'Connell, JX.; Rosenberg, AE. (Oct 1998). "Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants.". Am J Surg Pathol 22 (10): 1222-7. PMID 9777984.
  4. Yamashita, H.; Endo, K.; Takeda, C.; Teshima, R.; Osaki, M.; Yoshida, H. (May 2013). "Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression.". Skeletal Radiol. doi:10.1007/s00256-013-1641-4. PMID 23685711.