Difference between revisions of "Intramuscular myxoma"

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| Width      =  
| Width      =  
| Caption    = Intramuscular myxoma.  
| Caption    = Intramuscular myxoma.  
| Micro      =
| Micro      = myxoid stroma with bland stellate cells and/or bland spindle cells, intramuscular, usu. hypervascular and hypercellular
| Subtypes  =
| Subtypes  = hypercellular, hypervascular
| LMDDx      = [[myxoid lesions]]
| LMDDx      = [[myxoid lesions]]
| Stains    =
| Stains    =
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| Gross      =
| Gross      =
| Grossing  =
| Grossing  =
| Site      = [[Soft tissue]]
| Site      = [[soft tissue]]
| Assdx      =
| Assdx      =
| Syndromes  =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Signs      =
| Symptoms  =
| Symptoms  =
| Prevalence =
| Prevalence = rare
| Bloodwork  =
| Bloodwork  =
| Rads      =
| Rads      =
| Endoscopy  =
| Endoscopy  =
| Prognosis  =
| Prognosis  = benign, rarely recur
| Other      =
| Other      =
| ClinDDx    =
| ClinDDx    =
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==Microscopic==
==Microscopic==
Features:<ref name=pmid15663047/>
Features:<ref name=pmid15663047/><ref name=pmid9777984/>
*Myxoid stroma.
*Myxoid stroma - '''key feature'''
**Paucicellular.
*Bland stellate or spindle cells.  
**Scant vascularity.  
**Typically paucicellular.
*Contained within skeletal muscle.
**Usually with scant vascularity.
*Contained within skeletal muscle - '''essential'''.


DDx:
Note:
*† A hypercellular variant exists.
*‡ A hypervascular variant exists.
 
DDx:<ref name=pmid9777984>{{Cite journal  | last1 = Nielsen | first1 = GP. | last2 = O'Connell | first2 = JX. | last3 = Rosenberg | first3 = AE. | title = Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. | journal = Am J Surg Pathol | volume = 22 | issue = 10 | pages = 1222-7 | month = Oct | year = 1998 | doi =  | PMID = 9777984 }}</ref>
*[[Low-grade fibromyxoid sarcoma]].<ref name=pmid23685711>{{Cite journal  | last1 = Yamashita | first1 = H. | last2 = Endo | first2 = K. | last3 = Takeda | first3 = C. | last4 = Teshima | first4 = R. | last5 = Osaki | first5 = M. | last6 = Yoshida | first6 = H. | title = Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. | journal = Skeletal Radiol | volume =  | issue =  | pages =  | month = May | year = 2013 | doi = 10.1007/s00256-013-1641-4 | PMID = 23685711 }}</ref>
*[[Low-grade fibromyxoid sarcoma]].<ref name=pmid23685711>{{Cite journal  | last1 = Yamashita | first1 = H. | last2 = Endo | first2 = K. | last3 = Takeda | first3 = C. | last4 = Teshima | first4 = R. | last5 = Osaki | first5 = M. | last6 = Yoshida | first6 = H. | title = Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. | journal = Skeletal Radiol | volume =  | issue =  | pages =  | month = May | year = 2013 | doi = 10.1007/s00256-013-1641-4 | PMID = 23685711 }}</ref>
*[[Myxoid liposarcoma]].
*[[Myxofibrosarcoma]]
*[[Juxta-articular myxoma]].


===Images===
===Images===
<gallery>
<gallery>
Image: IntramuscularMyxoma.JPG | Intramuscular myxoma. (WC)
Image: Intramuscular myxoma - low mag.jpg | Low mag. (WC/Nephron)
Image: Intramuscular myxoma - low mag.jpg | Low mag. (WC/Nephron)
Image: Intramuscular myxoma - intermed mag.jpg | Intermed. mag. (WC/Nephron)
Image: Intramuscular myxoma - intermed mag.jpg | Intermed. mag. (WC/Nephron)
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==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Soft tissue lesions]]
[[Category:Soft tissue lesions]]

Latest revision as of 20:54, 5 July 2013

Intramuscular myxoma
Diagnosis in short

Intramuscular myxoma.

LM myxoid stroma with bland stellate cells and/or bland spindle cells, intramuscular, usu. hypervascular and hypercellular
Subtypes hypercellular, hypervascular
LM DDx myxoid lesions
Site soft tissue

Prevalence rare
Prognosis benign, rarely recur

Intramuscular myxoma is an uncommon benign intramuscular myxoid lesion.

General

  • Rare.[1]
  • Usually do not recur.[2]
  • Present as a mass.[2]

Gross

  • Usually thigh muscles.[2]

Microscopic

Features:[1][3]

  • Myxoid stroma - key feature
  • Bland stellate or spindle cells.
    • Typically paucicellular. †
    • Usually with scant vascularity. ‡
  • Contained within skeletal muscle - essential.

Note:

  • † A hypercellular variant exists.
  • ‡ A hypervascular variant exists.

DDx:[3]

Images

See also

References

  1. 1.0 1.1 Charron, P.; Smith, J. (Dec 2004). "Intramuscular myxomas: a clinicopathologic study with emphasis on surgical management.". Am Surg 70 (12): 1073-7. PMID 15663047.
  2. 2.0 2.1 2.2 Silver, WP.; Harrelson, JM.; Scully, SP. (Oct 2002). "Intramuscular myxoma: a clinicopathologic study of 17 patients.". Clin Orthop Relat Res (403): 191-7. PMID 12360026.
  3. 3.0 3.1 Nielsen, GP.; O'Connell, JX.; Rosenberg, AE. (Oct 1998). "Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants.". Am J Surg Pathol 22 (10): 1222-7. PMID 9777984.
  4. Yamashita, H.; Endo, K.; Takeda, C.; Teshima, R.; Osaki, M.; Yoshida, H. (May 2013). "Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression.". Skeletal Radiol. doi:10.1007/s00256-013-1641-4. PMID 23685711.