Difference between revisions of "Interstitial cystitis"

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'''Interstitial cystitis''' is a benign painful pathology of the [[urothelium]].
'''Interstitial cystitis''' is a benign painful pathology of the [[urinary bladder]].


It is also known as '''painful bladder syndrome'''.<ref name=pmid21609485>{{Cite journal  | last1 = Tanaka | first1 = T. | last2 = Nitta | first2 = Y. | last3 = Morimoto | first3 = K. | last4 = Nishikawa | first4 = N. | last5 = Nishihara | first5 = C. | last6 = Tamada | first6 = S. | last7 = Kawashima | first7 = H. | last8 = Nakatani | first8 = T. | title = Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan. | journal = BMC Urol | volume = 11 | issue =  | pages = 11 | month =  | year = 2011 | doi = 10.1186/1471-2490-11-11 | PMID = 21609485 }}</ref><ref name=pmid21568251>{{Cite journal  | last1 = French | first1 = LM. | last2 = Bhambore | first2 = N. | title = Interstitial cystitis/painful bladder syndrome. | journal = Am Fam Physician | volume = 83 | issue = 10 | pages = 1175-81 | month = May | year = 2011 | doi =  | PMID = 21568251 }}</ref>
It is also known as '''painful bladder syndrome'''.<ref name=pmid21609485>{{Cite journal  | last1 = Tanaka | first1 = T. | last2 = Nitta | first2 = Y. | last3 = Morimoto | first3 = K. | last4 = Nishikawa | first4 = N. | last5 = Nishihara | first5 = C. | last6 = Tamada | first6 = S. | last7 = Kawashima | first7 = H. | last8 = Nakatani | first8 = T. | title = Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan. | journal = BMC Urol | volume = 11 | issue =  | pages = 11 | month =  | year = 2011 | doi = 10.1186/1471-2490-11-11 | PMID = 21609485 }}</ref><ref name=pmid21568251>{{Cite journal  | last1 = French | first1 = LM. | last2 = Bhambore | first2 = N. | title = Interstitial cystitis/painful bladder syndrome. | journal = Am Fam Physician | volume = 83 | issue = 10 | pages = 1175-81 | month = May | year = 2011 | doi =  | PMID = 21568251 }}</ref>
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==General==
==General==
*Chronic cystitis, culture negative.
*Chronic cystitis, culture negative.
*Treatment difficult.<ref name=pmid21609485/>


Epidemiology:<ref name=pmid21568251/>
Epidemiology:<ref name=pmid21568251/>
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*Frequency.
*Frequency.
*Pain.
*Pain.
Treatment:
*Difficult.<ref name=pmid21609485/>
*Fulguration of ulcers (if present) may provide symptomatic relief.<ref name=pmid23083651/>


==Gross==
==Gross==
*+/-Ulceration.
*+/-Ulceration.
Note:
*Fulguration of ulcers (if present) may provide symptomatic relief.<ref name=pmid23083651/>


==Microscopic==
==Microscopic==
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DDx:
DDx:
*[[Urothelial carcinoma in situ|Urothelial CIS]].
*[[Urothelial carcinoma in situ|Urothelial CIS]].
==Sign out==
<pre>
Urinary Bladder, Biopsy:
- Inflamed subepithelial tissue; NEGATIVE for appreciable amount of urothelium.
- NEGATIVE for evidence of malignancy.
Comment:
Deepers were cut (x4) and are non-contributory.
</pre>


==See also==
==See also==

Latest revision as of 14:00, 18 April 2016

Interstitial cystitis is a benign painful pathology of the urinary bladder.

It is also known as painful bladder syndrome.[1][2]

Hunner ulcer redirects here.[3]

General

  • Chronic cystitis, culture negative.

Epidemiology:[2]

  • Women > men.

Symptoms:[2]

  • Urgency.
  • Frequency.
  • Pain.

Treatment:

  • Difficult.[1]
  • Fulguration of ulcers (if present) may provide symptomatic relief.[3]

Gross

  • +/-Ulceration.

Microscopic

Features:[4]

  • +/-Ulceration (uncommon).

Note:

DDx:

Sign out

Urinary Bladder, Biopsy:
- Inflamed subepithelial tissue; NEGATIVE for appreciable amount of urothelium.
- NEGATIVE for evidence of malignancy.

Comment:
Deepers were cut (x4) and are non-contributory.

See also

References

  1. 1.0 1.1 Tanaka, T.; Nitta, Y.; Morimoto, K.; Nishikawa, N.; Nishihara, C.; Tamada, S.; Kawashima, H.; Nakatani, T. (2011). "Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan.". BMC Urol 11: 11. doi:10.1186/1471-2490-11-11. PMID 21609485.
  2. 2.0 2.1 2.2 French, LM.; Bhambore, N. (May 2011). "Interstitial cystitis/painful bladder syndrome.". Am Fam Physician 83 (10): 1175-81. PMID 21568251.
  3. 3.0 3.1 Hillelsohn, JH.; Rais-Bahrami, S.; Friedlander, JI.; Okhunov, Z.; Kashan, M.; Rosen, L.; Moldwin, RM. (Dec 2012). "Fulguration for Hunner ulcers: long-term clinical outcomes.". J Urol 188 (6): 2238-41. doi:10.1016/j.juro.2012.08.013. PMID 23083651.
  4. Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 124. ISBN 978-0443066771.