Difference between revisions of "Inflammatory skin disorders"

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==Necrobiotic xanthogranuloma==
==Necrobiotic xanthogranuloma==
*Abbreviated ''NXG''.
*Abbreviated ''NXG''.
===General===
{{Main|Necrobiotic xanthogranuloma}}
*Usually elderly.<ref name=Ref_Derm629>{{Ref Derm|629}}</ref>
 
===Gross===
Features:
*Periorbital - classic location.<ref name=pmid17544963>{{Cite journal  | last1 = Fernández-Herrera | first1 = J. | last2 = Pedraz | first2 = J. | title = Necrobiotic xanthogranuloma. | journal = Semin Cutan Med Surg | volume = 26 | issue = 2 | pages = 108-13 | month = Jun | year = 2007 | doi = 10.1016/j.sder.2007.02.008 | PMID = 17544963 }}</ref>
 
===Microscopic===
Features:<ref name=Ref_Derm629>{{Ref Derm|629}}</ref>
*"Necrobiotic granuloma":
**Palisading granuloma with a core collagen-like material.
*+/-Cholesterol clefts - common.
*+/-[[Touton giant cell]]s.
*+/-Atypical foreign body-type giant cells +/- asteroid bodies.
 
DDx:
*[[Granuloma annulare]].
*[[Necrobiosis lipoidica]] - has plasma cells.
*Granuloma-forming infections - positive stains for microorganisms.
 
Image:
*[http://commons.wikimedia.org/wiki/File:Asteroid_bodies_high_mag_cropped.jpg Asteroid body (WC)].


=DDx for pattern=
=DDx for pattern=
48,466

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