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Hyperplastic polyp with perineuromatous stroma (view source)
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'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign [[colorectal polyp]]. | '''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign [[colorectal polyp]]. | ||
It may be referred to as '''[[perineurioma]]''' and '''fibroblastic polyp'''.<ref name=pmid18520438>{{cite journal | | It may be referred to as '''[[perineurioma]]''' and '''fibroblastic polyp'''.<ref name=pmid18520438>{{cite journal |authors=Groisman GM, Polak-Charcon S |title=Fibroblastic polyp of the colon and colonic perineurioma: 2 names for a single entity? |journal=Am J Surg Pathol |volume=32 |issue=7 |pages=1088–94 |date=July 2008 |pmid=18520438 |doi=10.1097/PAS.0b013e318160df3f |url=}}</ref> | ||
==General== | ==General== | ||
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==IHC== | ==IHC== | ||
Features:<ref name=pmid15104300>{{cite journal | | Features:<ref name=pmid15104300>{{cite journal |authors=Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D |title=Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study |journal=Am J Surg Pathol |volume=28 |issue=3 |pages=374–8 |date=March 2004 |pmid=15104300 |doi=10.1097/00000478-200403000-00010 |url=}}</ref> | ||
*Vimentin +ve. | *Vimentin +ve. | ||
*SMA -ve. | *SMA -ve. | ||
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*S-100 -ve | *S-100 -ve | ||
*EMA -ve. | *EMA -ve. | ||
==Sign out== | |||
<pre> | |||
Polyp, Colon at 35 cm, Polypectomy or Biopsy: | |||
- Hyperplastic polyp with perineuromatous stroma. | |||
</pre> | |||
===Micro=== | |||
The sections show a polypoid fragment of colonic-type serrated epithelium with small round glands at the deep aspect. Fibroblastic/perineuromatous type stroma is present and NSE NEGATIVE, S100 NEGATIVE and desmin NEGATIVE. The tissue is NEGATIVE for atypia and NEGATIVE for apparent proliferative activity. | |||
==See also== | ==See also== | ||