Difference between revisions of "Human immunodeficiency virus"

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'''Human immunodeficiency virus''', abbreviated '''HIV''', is the causative agent in ''acquire immune deficiency syndrome'' (AIDS) - unless you're a nutbar South African president called Thabo Mbeki.<ref>URL: [http://www.nytimes.com/2008/11/26/world/africa/26aids.html http://www.nytimes.com/2008/11/26/world/africa/26aids.html]. Accessed on: 19 September 2010.</ref>
'''Human immunodeficiency virus''', abbreviated '''HIV''', is generally held to be the causative agent in '''acquired immune deficiency syndrome''', commonly abbreviated '''AIDS'''.


It is associated with a very wide range of pathology including neoplasias and infections.
It is associated with a very wide range of pathology including neoplasias and infections.
 
=HIV-associated pathology=
==Neoplasia==
==Neoplasia==
*[[Kaposi sarcoma]].
*[[Kaposi sarcoma]].
*[[Hodgkin lymphoma]].
*[[Hodgkin lymphoma]].
*Primary effusion lymphoma<ref name=pmid15256448>{{cite journal |author=Staudt MR, Kanan Y, Jeong JH, Papin JF, Hines-Boykin R, Dittmer DP |title=The tumor microenvironment controls primary effusion lymphoma growth in vivo |journal=Cancer Res. |volume=64 |issue=14 |pages=4790–9 |year=2004 |month=July |pmid=15256448 |doi=10.1158/0008-5472.CAN-03-3835 |url=}}</ref> - considered to be a special subtype of [[DLBCL]].<ref>{{Ref PCPBoD8|322}}</ref>
*[[Primary effusion lymphoma]]<ref name=pmid15256448>{{cite journal |author=Staudt MR, Kanan Y, Jeong JH, Papin JF, Hines-Boykin R, Dittmer DP |title=The tumor microenvironment controls primary effusion lymphoma growth in vivo |journal=Cancer Res. |volume=64 |issue=14 |pages=4790–9 |year=2004 |month=July |pmid=15256448 |doi=10.1158/0008-5472.CAN-03-3835 |url=}}</ref> - considered to be a special subtype of [[DLBCL]].<ref>{{Ref PCPBoD8|322}}</ref>
*[[Leiomyoma]] and [[leiomyosarcoma]] in association with [[EBV]].<ref name=pmid8880205>{{Cite journal  | last1 = McClain | first1 = KL. | last2 = Joshi | first2 = VV. | last3 = Murphy | first3 = SB. | title = Cancers in children with HIV infection. | journal = Hematol Oncol Clin North Am | volume = 10 | issue = 5 | pages = 1189-201 | month = Oct | year = 1996 | doi =  | PMID = 8880205 }}</ref>


==Other==
==Other==
===Miscellaneous===
*[[Haemophagocytic syndrome]].
*[[Haemophagocytic syndrome]].
*[[Castleman disease]], plasma cell variant.  
*[[Castleman disease]], plasma cell variant.  
===Renal pathology===
*[[Collapsing glomerulopathy]].
*[[Membranoproliferative glomerulonephritis]].


==Infections==
==Infections==
*[[Pneumocystis jiroveci pneumonia]] (PCP).
*[[Pneumocystis jiroveci pneumonia]] (PCP).
*[[Isosporiasis]] - caused by Isospora belli.<ref>URL: [http://www.pathology.med.umich.edu/greensonlab/DECUNKNOWN.HTML http://www.pathology.med.umich.edu/greensonlab/DECUNKNOWN.HTML]. Accessed on: 25 February 2011.</ref>
*[[Toxoplasmosis]].
*[[Toxoplasmosis]].
*[[Cryptosporidiosis]].
*[[Cryptosporidiosis]].
*[[Tuberculosis]].
*[[Tuberculosis]].
*Mycobacterium avium complex (MAC).
*[[Mycobacterium avium complex]] (MAC).
**Consists of: Mycobacterium avium and Mycobacterium intracellulare.
**Consists of: Mycobacterium avium and Mycobacterium intracellulare.
***MAC = MAI (Mycobacterium avium intracellulare).<ref>URL: [http://www.pathology.med.umich.edu/greensonlab/JANUNKNOWN.HTML http://www.pathology.med.umich.edu/greensonlab/JANUNKNOWN.HTML]. Accessed on: 25 February 2011.</ref> (???)
***MAC = MAI (Mycobacterium avium intracellulare).<ref>URL: [http://www.pathology.med.umich.edu/greensonlab/JANUNKNOWN.HTML http://www.pathology.med.umich.edu/greensonlab/JANUNKNOWN.HTML]. Accessed on: 25 February 2011.</ref>{{fact}}
 
Less common:
*[[Progressive multifocal leukoencephalopathy]].
*[[Isosporiasis]] - caused by Isospora belli.<ref>URL: [http://www.pathology.med.umich.edu/greensonlab/DECUNKNOWN.HTML http://www.pathology.med.umich.edu/greensonlab/DECUNKNOWN.HTML]. Accessed on: 25 February 2011.</ref>
 
=AIDS-defining conditions=
There is a long list of AIDS-defining illnesses.<ref name=pmid19052530>{{cite journal |author=Schneider E, Whitmore S, Glynn KM, Dominguez K, Mitsch A, McKenna MT |title=Revised surveillance case definitions for HIV infection among adults, adolescents, and children aged <18 months and for HIV infection and AIDS among children aged 18 months to <13 years--United States, 2008 |journal=MMWR Recomm Rep |volume=57 |issue=RR-10 |pages=1–12 |year=2008 |month=December |pmid=19052530 |doi= |url=http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5710a1.htm}}</ref>
 
==Selected infectious AIDS-defining illnesses==
*[[Pneumocystis jiroveci pneumonia]].
*[[Candidiasis of esophagus]].
*[[Tuberculosis]]
 
==Selected neoplastic AIDS-defining illnesses==
*[[Kaposi sarcoma]].
*Invasive cervical cancer.
*[[Burkitt lymphoma]].


==See also==
=See also=
*[[Viruses]].
*[[Viruses]].
*[[Epstein-Barr virus-associated smooth muscle tumour]].


==References==
=References=
{{reflist|2}}
{{reflist|2}}


[[Category:Microorganisms]]
[[Category:Microorganisms]]

Latest revision as of 04:43, 30 September 2014

Human immunodeficiency virus, abbreviated HIV, is generally held to be the causative agent in acquired immune deficiency syndrome, commonly abbreviated AIDS.

It is associated with a very wide range of pathology including neoplasias and infections.

HIV-associated pathology

Neoplasia

Other

Miscellaneous

Renal pathology

Infections

Less common:

AIDS-defining conditions

There is a long list of AIDS-defining illnesses.[6]

Selected infectious AIDS-defining illnesses

Selected neoplastic AIDS-defining illnesses

See also

References

  1. Staudt MR, Kanan Y, Jeong JH, Papin JF, Hines-Boykin R, Dittmer DP (July 2004). "The tumor microenvironment controls primary effusion lymphoma growth in vivo". Cancer Res. 64 (14): 4790–9. doi:10.1158/0008-5472.CAN-03-3835. PMID 15256448.
  2. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 322. ISBN 978-1416054542.
  3. McClain, KL.; Joshi, VV.; Murphy, SB. (Oct 1996). "Cancers in children with HIV infection.". Hematol Oncol Clin North Am 10 (5): 1189-201. PMID 8880205.
  4. URL: http://www.pathology.med.umich.edu/greensonlab/JANUNKNOWN.HTML. Accessed on: 25 February 2011.
  5. URL: http://www.pathology.med.umich.edu/greensonlab/DECUNKNOWN.HTML. Accessed on: 25 February 2011.
  6. Schneider E, Whitmore S, Glynn KM, Dominguez K, Mitsch A, McKenna MT (December 2008). "Revised surveillance case definitions for HIV infection among adults, adolescents, and children aged <18 months and for HIV infection and AIDS among children aged 18 months to <13 years--United States, 2008". MMWR Recomm Rep 57 (RR-10): 1–12. PMID 19052530. http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5710a1.htm.