Difference between revisions of "Hepatitis B"
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*May lead to [[hepatocellular carcinoma]] without [[cirrhosis]]. | *May lead to [[hepatocellular carcinoma]] without [[cirrhosis]]. | ||
*High prevalence. | *High prevalence. | ||
*Diagnosis is by serology. | *Diagnosis is by serology - details of serologic testing are in the ''[[Medical_liver_disease#Hepatitis_B|medical liver disease article]]''. | ||
*A vaccination is available and done routinely in a many jurisdictions.<ref>{{Cite journal | last1 = Leuridan | first1 = E. | last2 = Van Damme | first2 = P. | title = Hepatitis B and the need for a booster dose. | journal = Clin Infect Dis | volume = 53 | issue = 1 | pages = 68-75 | month = Jul | year = 2011 | doi = 10.1093/cid/cir270 | PMID = 21653306 }}</ref> | *A vaccination is available and done routinely in a many jurisdictions.<ref>{{Cite journal | last1 = Leuridan | first1 = E. | last2 = Van Damme | first2 = P. | title = Hepatitis B and the need for a booster dose. | journal = Clin Infect Dis | volume = 53 | issue = 1 | pages = 68-75 | month = Jul | year = 2011 | doi = 10.1093/cid/cir270 | PMID = 21653306 }}</ref> | ||
Revision as of 17:42, 25 June 2016
Hepatitis B is a relatively common medical liver disease caused by the hepatitis B virus.
General
- May lead to hepatocellular carcinoma without cirrhosis.
- High prevalence.
- Diagnosis is by serology - details of serologic testing are in the medical liver disease article.
- A vaccination is available and done routinely in a many jurisdictions.[1]
Associated pathology:
Microscopic
Features:
- Lobular inflammation - this is non-specific finding.
- Hepatocyte necrosis:
- Necrotic hepatocytes look a lot like neutrophils - however:
- Cytoplasm is more pink.
- Round apoptotic bodies.
- Necrotic hepatocytes look a lot like neutrophils - however:
- Hepatocyte necrosis:
- Ground glass hepatocytes - important.
DDx:
Image
GGH - high mag. (WC)
IHC
- Hepatitis B +ve.
See also
References
- ↑ Leuridan, E.; Van Damme, P. (Jul 2011). "Hepatitis B and the need for a booster dose.". Clin Infect Dis 53 (1): 68-75. doi:10.1093/cid/cir270. PMID 21653306.