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Difference between revisions of "Hairy cell leukemia"
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*Good prognosis (with treatment), though (likely) not curable. | *Good prognosis (with treatment), though (likely) not curable. | ||
==Gross== | |||
Features:<ref name=Ref_PCPBoD8_326>{{Ref PCPBoD8|326}}</ref> | Features:<ref name=Ref_PCPBoD8_326>{{Ref PCPBoD8|326}}</ref> | ||
*Huge beefy red [[spleen]]. | *Huge beefy red [[spleen]]. | ||
**Red as white pulp obliterated. | **Red as white pulp obliterated. | ||
==Microscopic== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/200580-diagnosis http://emedicine.medscape.com/article/200580-diagnosis]. Accessed on: 18 August 2010.</ref> | Features:<ref>URL: [http://emedicine.medscape.com/article/200580-diagnosis http://emedicine.medscape.com/article/200580-diagnosis]. Accessed on: 18 August 2010.</ref> | ||
*Small cells (10-20 micrometers) with "Fried egg"-like appearance: | *Small cells (10-20 micrometers) with "Fried egg"-like appearance: | ||
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*[[Hepatosplenic T-cell lymphoma]]. | *[[Hepatosplenic T-cell lymphoma]]. | ||
===Images=== | |||
<gallery> | <gallery> | ||
Image:Hairy_cell_leukemia.jpg | HCL - blood film. (WC) | Image:Hairy_cell_leukemia.jpg | HCL - blood film. (WC) | ||
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*[http://webpathology.com/image.asp?case=380&n=3 HCL in the spleen (webpathology.com)]. | *[http://webpathology.com/image.asp?case=380&n=3 HCL in the spleen (webpathology.com)]. | ||
==IHC== | |||
Features:<ref>URL: [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cmed&part=A34022&rendertype=table&id=A34029 http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cmed&part=A34022&rendertype=table&id=A34029]. Accessed on: 20 August 2010.</ref> | Features:<ref>URL: [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cmed&part=A34022&rendertype=table&id=A34029 http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cmed&part=A34022&rendertype=table&id=A34029]. Accessed on: 20 August 2010.</ref> | ||
*CD20 +ve, CD11c+ve, CD25 +ve, CD103 +ve, CD123 +ve, cyclin D1 +ve, DBA44 +ve | *CD20 +ve, CD11c+ve, CD25 +ve, CD103 +ve, CD123 +ve, cyclin D1 +ve, DBA44 +ve | ||
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*CD19 +ve, CD11c +ve, FMC7 +ve. | *CD19 +ve, CD11c +ve, FMC7 +ve. | ||
===References | ==See also== | ||
*[[Small cell lymphomas]]. | |||
==References== | |||
{{Reflist}} | {{Reflist}} | ||
[[Category: Haematopathology]] | [[Category: Haematopathology]] | ||