Glycoprotein non-metastatic B

From Libre Pathology
Revision as of 13:29, 26 March 2024 by Michael (talk | contribs)
Jump to navigation Jump to search

Glycoprotein non-metastatic B, abbreviated GPNMB, is an immunostain.

It is typically positive in TSC1/TSC2/MTOR mutated renal cell carcinomas.[1]

Positive

Negative

References

  1. Li H, Argani P, Halper-Stromberg E, Lotan TL, Merino MJ, Reuter VE, Matoso A (November 2023). "Positive GPNMB Immunostaining Differentiates Renal Cell Carcinoma With Fibromyomatous Stroma Associated With TSC1/2/MTOR Alterations From Others". Am J Surg Pathol 47 (11): 1267–1273. doi:10.1097/PAS.0000000000002117. PMID 37661807.