Difference between revisions of "Glycoprotein non-metastatic B"

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*[[Renal cell carcinoma with fibromyomatous stroma]].
*[[Renal cell carcinoma with fibromyomatous stroma]].


==Negative
==Negative==
*[[Clear cell renal cell carcinoma]].
*[[Clear cell renal cell carcinoma]].
*[[Papillary renal cell carcinoma]].
*[[Papillary renal cell carcinoma]].

Revision as of 13:29, 26 March 2024

Glycoprotein non-metastatic B, abbreviated GPNMB, is an immunostain.

It is typically positive in TSC1/TSC2/MTOR mutated renal cell carcinomas.[1]

Positive

Negative

References

  1. Li H, Argani P, Halper-Stromberg E, Lotan TL, Merino MJ, Reuter VE, Matoso A (November 2023). "Positive GPNMB Immunostaining Differentiates Renal Cell Carcinoma With Fibromyomatous Stroma Associated With TSC1/2/MTOR Alterations From Others". Am J Surg Pathol 47 (11): 1267–1273. doi:10.1097/PAS.0000000000002117. PMID 37661807.