Difference between revisions of "Germ cell tumours"

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==Mixed germ cell tumour==
==Mixed germ cell tumour==
===General===
{{Main|Mixed germ cell tumour}}
*60% of GCTs are mixed.
 
Common combinations:
# Teratoma + embryonal carcinoma + endodermal sinus tumour (yolk sac tumour) (TEE).
# Seminoma + embryonal (SE).
# Teratoma + embryonal +(TE).
 
Memory device: ''TEE'' + all combinations have embryonal carcinoma.
===Microscopic===
Features:
*Depends on components.
 
Notes:
*If one cannot identify the component... it is probably yolk sac as this has so many different patterns.
 
====Images====
<gallery>
Image:Mixed_germ_cell_tumour_-_intermed_mag.jpg | Mixed GCT - intermed mag. (WC/Nephron)
Image:Mixed germ cell tumour - high mag.jpg | Mixed GCT - high mag. (WC/Nephron)
</gallery>
www:
*[http://path.upmc.edu/cases/case192/micro.html Mixed germ cell tumour - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case356.html Mixed germ cell tumour - several cases (upmc.edu)].
 
===IHC===
*Beta-hCG +ve - if syncytiotrophoblasts are present.
*AFP +ve - a yolk sac tumour component is present.
*GFAP +ve - if neuroepithelium is present.


==See also==
==See also==
48,466

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