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Difference between revisions of "Gastric xanthoma"
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→IHC: +SO
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_GLP111>{{Ref GLP|111}}</ref> | Features:<ref name=Ref_GLP111>{{Ref GLP|111}}</ref> | ||
*Collections of | *Collections of lipid-laden macrophages within the gastric lamina propria. | ||
DDx: | DDx: | ||
*[[Signet ring cell carcinoma]].<ref name=pmid6284833>{{Cite journal | last1 = Drude | first1 = RB. | last2 = Balart | first2 = LA. | last3 = Herrington | first3 = JP. | last4 = Beckman | first4 = EN. | last5 = Burns | first5 = TW. | title = Gastric xanthoma: histologic similarity to signet ring cell carcinoma. | journal = J Clin Gastroenterol | volume = 4 | issue = 3 | pages = 217-21 | month = Jun | year = 1982 | doi = | PMID = 6284833 }}</ref> | *[[Signet ring cell carcinoma]].<ref name=pmid6284833>{{Cite journal | last1 = Drude | first1 = RB. | last2 = Balart | first2 = LA. | last3 = Herrington | first3 = JP. | last4 = Beckman | first4 = EN. | last5 = Burns | first5 = TW. | title = Gastric xanthoma: histologic similarity to signet ring cell carcinoma. | journal = J Clin Gastroenterol | volume = 4 | issue = 3 | pages = 217-21 | month = Jun | year = 1982 | doi = | PMID = 6284833 }}</ref> | ||
*[[Whipple disease]]. | *[[Whipple disease]]. | ||
*MAC infection. | *[[MAC infection]]. | ||
===Images=== | ===Images=== | ||
| Line 68: | Line 68: | ||
*Panker (AE1/AE3) -ve. | *Panker (AE1/AE3) -ve. | ||
**To exclude carcinoma. | **To exclude carcinoma. | ||
==Sign out== | |||
<pre> | |||
Stomach, Cardia Lesion, Biopsy: | |||
- Polypoid gastric xanthoma. | |||
- NEGATIVE for Helicobacter-like organisms. | |||
- NEGATIVE for intestinal metaplasia. | |||
- NEGATIVE for dysplasia and NEGATIVE for malignancy. | |||
Comment: | |||
The histiocytes in were demonstrated with a CD68 immunostain. | |||
An AE1/AE3 immunostain and a Ki-67 immunostain have a benign pattern. | |||
</pre> | |||
==See also== | ==See also== | ||