Difference between revisions of "Gastric xanthoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Gastric_Xanthelasma,_HE_03.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Gastric xanthoma. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = gastric lamina propria with lipid-laden macrophages | | Micro = gastric lamina propria with lipid-laden macrophages | ||
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===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image:Gastric Xanthelasma, HE 01.jpg|GX. (WC) | |||
Image:Gastric Xanthelasma, HE 02.jpg|GX. (WC) | |||
Image:Gastric Xanthelasma, HE 03.jpg|GX. (WC) | |||
Image:Gastric Xanthelasma, CD68.jpg|GX - CD68. (WC) | |||
</gallery> | |||
<gallery> | |||
Image:Xanthoma_histology.jpg | Xanthoma. (WC) | |||
</gallery> | </gallery> | ||
www: | www: | ||
Revision as of 03:25, 13 January 2014
| Gastric xanthoma | |
|---|---|
| Diagnosis in short | |
 Gastric xanthoma. H&E stain. | |
|
| |
| LM | gastric lamina propria with lipid-laden macrophages |
| LM DDx | signet ring cell carcinoma, Whipple disease, MAI infection |
| IHC | CD68 +ve, AE1/AE3 -ve |
| Gross | yellowish nodule or plaque - usu. lesser curvature |
| Site | stomach |
|
| |
| Prevalence | uncommon |
| Prognosis | benign |
Gastric xanthoma, abbreviated GX, is an uncommon benign lesion of the stomach.
It is also known as xanthelasma and stomach lipidosis.
General
- Uncommon.
- Benign.
Gross/endoscopic
Microscopic
Features:[1]
- Collections of gastric lamina propria with lipid-laden macrophages.
DDx:
- Signet ring cell carcinoma.[2]
- Whipple disease.
- MAC infection.
Images
GX. (WC)
GX. (WC)
GX. (WC)
GX - CD68. (WC)
Xanthoma. (WC)
www:
IHC
- CD68 +ve.
- Panker (AE1/AE3) -ve.
- To exclude carcinoma.
See also
References
- ↑ 1.0 1.1 Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 111. ISBN 978-0443066573.
- ↑ 2.0 2.1 Drude, RB.; Balart, LA.; Herrington, JP.; Beckman, EN.; Burns, TW. (Jun 1982). "Gastric xanthoma: histologic similarity to signet ring cell carcinoma.". J Clin Gastroenterol 4 (3): 217-21. PMID 6284833.