Difference between revisions of "Gastric adenocarcinoma and proximal polyposis of the stomach"
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==See also== | ==See also== | ||
*[[Stomach]]. | *[[Stomach]]. | ||
*[[Gastric adenocarcinoma]]. | |||
==References== | ==References== |
Latest revision as of 20:51, 12 December 2019
Gastric adenocarcinoma and proximal polyposis of the stomach, abbreviated GAPPS, is a rare syndrome characterized by fundic gland polyps and gastric adenocarcinoma.[1][2]
General
Criteria
Features - all required:[1]
- Polyps of stomach - body and fundus only.
- >100 polyps in index case or >30 polyps in first degree relative.
- Histology predominantly fundic gland polyps - some with dysplasia or adenocarcinoma in background.
- No colorectal or duodenal polyposis.
- Exclusion of other heritable polyposis syndrome involving the stomach, proton pump inhibitor (PPI) use.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Rudloff, U. (2018). "Gastric adenocarcinoma and proximal polyposis of the stomach: diagnosis and clinical perspectives.". Clin Exp Gastroenterol 11: 447-459. doi:10.2147/CEG.S163227. PMID 30584346.
- ↑ Worthley, DL.; Phillips, KD.; Wayte, N.; Schrader, KA.; Healey, S.; Kaurah, P.; Shulkes, A.; Grimpen, F. et al. (May 2012). "Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome.". Gut 61 (5): 774-9. doi:10.1136/gutjnl-2011-300348. PMID 21813476.