Difference between revisions of "Fibrosing pleuritis"

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#redirect [[Medical_lung_diseases#Fibrosing_pleuritis]]
'''Fibrosing pleuritis''' is an uncommon benign condition that mimics [[malignant mesothelioma]].
 
It is also known as '''cryptogenic bilateral fibrosing pleuritis''' and '''fibrous pleurisy'''.
 
==General==
*Benign.
*No asbestos exposure.<ref name=pmid3166932>{{Cite journal  | last1 = Buchanan | first1 = DR. | last2 = Johnston | first2 = ID. | last3 = Kerr | first3 = IH. | last4 = Hetzel | first4 = MR. | last5 = Corrin | first5 = B. | last6 = Turner-Warwick | first6 = M. | title = Cryptogenic bilateral fibrosing pleuritis. | journal = Br J Dis Chest | volume = 82 | issue = 2 | pages = 186-93 | month = Apr | year = 1988 | doi =  | PMID = 3166932 }}</ref>
 
Clinical:<ref name=pmid3166932/>
*Pleural thickening on imaging.
*[[Pleural effusion]].
 
==Gross==
*Pleural thickening associated with a pleural effusion.
 
==Microscopic==
Features:<ref name=ultrapathorg>URL: [http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html]. Accessed on: 20 February 2012.</ref>
*Fibrosis.
**Spindle cells.
**Moderate cellularity.
*No [[necrosis]].
*Inflammation - lymphocytes.<ref name=pmid3166932/>
 
DDx:<ref name=pmid15559051>{{Cite journal  | last1 = Corson | first1 = JM. | title = Pathology of mesothelioma. | journal = Thorac Surg Clin | volume = 14 | issue = 4 | pages = 447-60 | month = Nov | year = 2004 | doi = 10.1016/j.thorsurg.2004.06.007 | PMID = 15559051 }}</ref>
*[[Mesothelioma]], desmoplastic.
**Mesothelioma should '''not''' be diagnosed on core biopsy.<ref name=ultrapathorg>URL: [http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html]. Accessed on: 20 February 2012.</ref>
 
==See also==
*[[Medical lung diseases]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Medical lung diseases]]

Revision as of 17:48, 2 September 2015

Fibrosing pleuritis is an uncommon benign condition that mimics malignant mesothelioma.

It is also known as cryptogenic bilateral fibrosing pleuritis and fibrous pleurisy.

General

  • Benign.
  • No asbestos exposure.[1]

Clinical:[1]

Gross

  • Pleural thickening associated with a pleural effusion.

Microscopic

Features:[2]

  • Fibrosis.
    • Spindle cells.
    • Moderate cellularity.
  • No necrosis.
  • Inflammation - lymphocytes.[1]

DDx:[3]

  • Mesothelioma, desmoplastic.
    • Mesothelioma should not be diagnosed on core biopsy.[2]

See also

References

  1. 1.0 1.1 1.2 Buchanan, DR.; Johnston, ID.; Kerr, IH.; Hetzel, MR.; Corrin, B.; Turner-Warwick, M. (Apr 1988). "Cryptogenic bilateral fibrosing pleuritis.". Br J Dis Chest 82 (2): 186-93. PMID 3166932.
  2. 2.0 2.1 URL: http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html. Accessed on: 20 February 2012.
  3. Corson, JM. (Nov 2004). "Pathology of mesothelioma.". Thorac Surg Clin 14 (4): 447-60. doi:10.1016/j.thorsurg.2004.06.007. PMID 15559051.