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Difference between revisions of "Extramammary Paget disease"
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Extramammary Paget disease (view source)
Revision as of 17:15, 20 December 2016
, 17:15, 20 December 2016no edit summary
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***Pagetoid squamous cell carcinoma in situ can lose HMW keratins and produce a LMW profile. | ***Pagetoid squamous cell carcinoma in situ can lose HMW keratins and produce a LMW profile. | ||
**Adenocarcinoma markers? - CEA, BerEP4 | **Adenocarcinoma markers? - CEA, BerEP4 | ||
**Nuclear differentiation markers? - p63 or p40 (squamous) vs GATA3 (adnexal) | **Nuclear differentiation markers? - p63 or [[p40]] (squamous) vs GATA3 (adnexal) | ||
*Is the lesion primary or secondary? | *Is the lesion primary or secondary? | ||
**Secondary extramammary Paget disease may be CK20 positive (urothelial or rectal) | **Secondary extramammary Paget disease may be CK20 positive (urothelial or rectal) | ||