E-cadherin

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E-cadherin is a common immunostain.

Mutations in the epithelial cadherin gene (abbreviated E-cadherin), also known as CDH1, are associated with hereditary diffuse gastric cancer syndrome.[1][2]

Negative

Images

Normal

Normal stain pattern:

  • Complete membrane staining.

Comment:

  • Partial loss is considered negative staining.

Images

See also

References