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Difference between revisions of "Diffuse lung diseases"
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→Hypersensitivity pneumonitis: +LIP
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(→Hypersensitivity pneumonitis: +LIP) |
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*[http://commons.wikimedia.org/wiki/File:Hypersensitivity_pneumonitis_high_mag.jpg Hypersensitivity pneumonitis - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Hypersensitivity_pneumonitis_high_mag.jpg Hypersensitivity pneumonitis - high mag. (WC)]. | ||
==Lymphocytic interstitial pneumonia== | |||
===General=== | |||
*Often abbreviated '''''LIP'''''. | |||
*Associated with autoimmune disorders ([[rheumatoid arthritis]], [[pernicious anemia]], Sjoegren syndrome)<ref>URL: [http://emedicine.medscape.com/article/299643-overview http://emedicine.medscape.com/article/299643-overview]. Accessed on: 2 June 2010.</ref> and immunodeficiency.<ref name=pmid16088689>{{cite journal |author=Nicholson AG |title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung |journal=Semin Respir Crit Care Med |volume=22 |issue=4 |pages=409–22 |year=2001 |month=August |pmid=16088689 |doi=10.1055/s-2001-17384 |url=}}</ref> | |||
*Associated with viral infections ([[HIV]], EBV, human T-cell leukemia virus (HTLV) type 1). | |||
===Gross=== | |||
*Location: basilar predominance. | |||
*Increased interstitial markings. | |||
===Microscopic=== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/299643-diagnosis http://emedicine.medscape.com/article/299643-diagnosis]. Accessed on: 2 June 2010.</ref> | |||
*Small mature lymphocytes (usually B cells).<ref name=afip_vol2_265>AFIP atlas of nontumour pathology. 2002. Vo. 2. P.265. ISBN 1-881041-79-4.</ref> | |||
*Plasma cells. | |||
*+/-Lymphoid follicles. | |||
Negatives: | |||
*No Vasculitis. | |||
*No necrosis. | |||
Image: [http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)]. | |||
DDx: | |||
*[[Lymphoma]]. | |||
*Follicular bronchitis/bronchiolitis. | |||
*Nodular lymphoid hyperplasia. | |||
**This is determined in part by radiology; it has nodules radiographically. | |||
=See also= | =See also= | ||