Difference between revisions of "Desquamative interstitial pneumonia"
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| Caption = | | Caption = | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = abundant brown pigmented airspace macrophages (smoker's macrophages), architecture preserved ("linear fibrosis") | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = amiodarone toxicity, fibrotic [[NSIP]], [[RBILD]] | | LMDDx = amiodarone toxicity, fibrotic [[NSIP]], [[RBILD]] | ||
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[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Diffuse lung diseases]] | |||
Revision as of 04:10, 21 March 2016
| Desquamative interstitial pneumonia | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | abundant brown pigmented airspace macrophages (smoker's macrophages), architecture preserved ("linear fibrosis") |
| LM DDx | amiodarone toxicity, fibrotic NSIP, RBILD |
| Site | lung - see diffuse lung diseases |
|
| |
| Associated Dx | smoking |
| Prevalence | uncommon |
| Treatment | stop smoking |
Desquamative interstitial pneumonia, abbreviated DIP, is a diffuse lung disease that is strongly associated with smoking.
General
Microscopic
Features:
- Abundant brown pigmented airspace macrophages - smoker's macrophages - key feature.
- Architecture preserved; "linear fibrosis".
Notes:
- Some fields of view may be indistinguishable from RBILD.
DDx:
Images
Stains
- Macrophages PAS +ve.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 93. ISBN 978-0781765275.