Difference between revisions of "Desquamative interstitial pneumonia"
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'''Desquamative interstitial pneumonia''', abbreviated ''DIP'', is a [[diffuse lung diseases|diffuse lung disease]] that is strongly associated with [[smoking]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
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| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = amiodarone toxicity, fibrotic [[NSIP]], [[RBILD]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[lung]] - see ''[[diffuse lung diseases]]'' | |||
| Assdx = [[smoking]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
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| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = stop smoking | |||
}} | |||
'''Desquamative interstitial pneumonia''', abbreviated '''DIP''', is a [[diffuse lung diseases|diffuse lung disease]] that is strongly associated with [[smoking]]. | |||
==General== | ==General== | ||
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*Amiodarone toxicity. | *Amiodarone toxicity. | ||
*Fibrotic [[NSIP]]. | *Fibrotic [[NSIP]]. | ||
*[[RBILD]]. | |||
Images | ===Images=== | ||
*[http://pathhsw5m54.ucsf.edu/case27/dip27.html DIP (ucsf.edu)]. | *[http://pathhsw5m54.ucsf.edu/case27/dip27.html DIP (ucsf.edu)]. | ||
Revision as of 04:08, 21 March 2016
| Desquamative interstitial pneumonia | |
|---|---|
| Diagnosis in short | |
| LM DDx | amiodarone toxicity, fibrotic NSIP, RBILD |
| Site | lung - see diffuse lung diseases |
|
| |
| Associated Dx | smoking |
| Prevalence | uncommon |
| Treatment | stop smoking |
Desquamative interstitial pneumonia, abbreviated DIP, is a diffuse lung disease that is strongly associated with smoking.
General
Microscopic
Features:
- Abundant brown pigmented airspace macrophages - smoker's macrophages - key feature.
- Architecture preserved; "linear fibrosis".
Notes:
- Some fields of view may be indistinguishable from RBILD.
DDx:
Images
Stains
- Macrophages PAS +ve.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 93. ISBN 978-0781765275.