Difference between revisions of "Desquamative interstitial pneumonia"
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'''Desquamative interstitial pneumonia''', abbreviated ''DIP'', is a [[diffuse lung diseases|diffuse lung disease]] that is strongly associated with [[smoking]]. | |||
==General== | |||
*Thought to be advanced ''[[RBILD]]''. | |||
*Strong association with smoking.<ref name=Ref_WMSP93>{{Ref WMSP|93}}</ref> | |||
**Treatment: stop smoking. | |||
==Microscopic== | |||
Features: | |||
*Abundant brown pigmented airspace macrophages - ''smoker's macrophages'' - '''key feature'''. | |||
*Architecture preserved; "linear fibrosis". | |||
Notes: | |||
*Some fields of view may be indistinguishable from [[RBILD]]. | |||
DDx: | |||
*Amiodarone toxicity. | |||
*Fibrotic [[NSIP]]. | |||
Images: | |||
*[http://pathhsw5m54.ucsf.edu/case27/dip27.html DIP (ucsf.edu)]. | |||
==Stains== | |||
*Macrophages [[PAS stain|PAS]] +ve. | |||
==See also== | |||
*[[Diffuse lung diseases]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 04:05, 21 March 2016
Desquamative interstitial pneumonia, abbreviated DIP, is a diffuse lung disease that is strongly associated with smoking.
General
Microscopic
Features:
- Abundant brown pigmented airspace macrophages - smoker's macrophages - key feature.
- Architecture preserved; "linear fibrosis".
Notes:
- Some fields of view may be indistinguishable from RBILD.
DDx:
- Amiodarone toxicity.
- Fibrotic NSIP.
Images:
Stains
- Macrophages PAS +ve.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 93. ISBN 978-0781765275.