Difference between revisions of "Dermatopathology"

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665 bytes removed ,  18:49, 1 September 2011
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=====Pre-malignant/malignant=====
=====Pre-malignant=====
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
! Entity
! Entity
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| [[squamous carcinoma]]
| [[squamous carcinoma]]
| [http://commons.wikimedia.org/wiki/File:Actinic_Keratosis,_H%26E.jpg (WC)]
| [http://commons.wikimedia.org/wiki/File:Actinic_Keratosis,_H%26E.jpg (WC)]
|-  
|}
=====Malignant=====
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
! Entity
! Key histologic feature
! Other features
! Clinical
! Stains/IHC
! DDx
! Other
! Image
|-
| [[Basal cell carcinoma]]
| [[Basal cell carcinoma]]
| basaloid cells with peripheral palisading, artificial cleft
| basaloid cells with peripheral palisading, artificial cleft
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| flaky appearance
| flaky appearance
| p63+, HMWK+ (???)
| p63+, HMWK+ (???)
| [[keratoacanathoma]]
| [[keratoacanthoma]]
| Other
| Other
| Image  
| Image  
|-
| [[Melanoma]]
| nuclear atypia (nucleoli), spindle and/or epithelioid morphology
| mitoses (esp. deep), +/-pigment, +/-nested arch., asymmetry, upward spread (into epidermis), epithelioid m. deep
| ABCD = Asymmetry, Borders poor demarc., Dolour dark, Diameter large
| S100+, Melan A+, HMB-45+, microphthalmia+, tyrosinase+
| [[melanocytic lesions]]
| may be familial, [[dysplastic nevus]]
| [http://en.wikipedia.org/wiki/File:Malignant_melanoma_%281%29_at_thigh_Case_01.jpg (WC)]
|- <!--
| [[Basal cell carcinoma]]
| basaloid cells with peripheral palisading, artificial cleft
| Other features
| pearly, telangiectasia
| none (???)
| [[trichoepithelioma]]
| assoc. [[nevoid basal cell carcinoma]]
| Image -->
|- <!--
| [[Squamous cell carcinoma]]
| Key histologic features
| Other features
| Clinical
| Stains/IHC
| DDx
| Other
| Image -->
|-
|-
| [[Melanoma]]
| [[Melanoma]]
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