Difference between revisions of "Cystic nephroma, adult type"

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#redirect [[Kidney_tumours#Cystic nephroma]]
'''Cystic nephroma''' is a rare [[kidney tumours|kidney tumour]].
 
Turbiner ''et al.''<ref name=pmid17414095>{{Cite journal  | last1 = Turbiner | first1 = J. | last2 = Amin | first2 = MB. | last3 = Humphrey | first3 = PA. | last4 = Srigley | first4 = JR. | last5 = De Leval | first5 = L. | last6 = Radhakrishnan | first6 = A. | last7 = Oliva | first7 = E. | title = Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term. | journal = Am J Surg Pathol | volume = 31 | issue = 4 | pages = 489-500 | month = Apr | year = 2007 | doi = 10.1097/PAS.0b013e31802bdd56 | PMID = 17414095 }}</ref>  have suggested that ''[[cystic nephroma]]'' and ''[[mixed epithelial and stromal tumour]] (MEST)'' are one tumour; the lumping term is ''renal epithelial and stromal tumour'' (abbreviated ''REST'').
 
==General==
*Rare.
 
==Gross==
*Bubble wrap-like appearance.
 
===Image===
<gallery>
Image:Bubble_Wrap.jpg| Bubble wrap. (WC)
</gallery>
==Microscopic==
Features:
*Cysts lined by simple epithelium with hobnailing - '''key feature'''.
*Stroma has an ovarian look:
**''Blue'' (basophilic).
**''Spindle cells''.
 
Notes:
*Parenchymal elements (e.g. glomueruli, tubules) are not found in the septa between the cysts.
===Images===
<gallery>
Image:Cystic_nephroma_low_mag.jpg |Cystic nephroma - low mag. (WC/Nephron)
Image:Cystic_nephroma_intermed_mag.jpg |Cystic nephroma - intermed. mag. (WC/Nephron)
</gallery>
 
==IHC==
Features:
*ER +ve.
*PR +ve.
*CD10 +ve.
 
==See also==
*[[Kidney tumours]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Kidney tumours]]

Revision as of 06:01, 14 November 2014

Cystic nephroma is a rare kidney tumour.

Turbiner et al.[1] have suggested that cystic nephroma and mixed epithelial and stromal tumour (MEST) are one tumour; the lumping term is renal epithelial and stromal tumour (abbreviated REST).

General

  • Rare.

Gross

  • Bubble wrap-like appearance.

Image

  • Bubble wrap. (WC)

Microscopic

Features:

  • Cysts lined by simple epithelium with hobnailing - key feature.
  • Stroma has an ovarian look:
    • Blue (basophilic).
    • Spindle cells.

Notes:

  • Parenchymal elements (e.g. glomueruli, tubules) are not found in the septa between the cysts.

Images

  • Cystic nephroma - low mag. (WC/Nephron)

  • Cystic nephroma - intermed. mag. (WC/Nephron)

IHC

Features:

  • ER +ve.
  • PR +ve.
  • CD10 +ve.

See also

References

  1. ↑ Turbiner, J.; Amin, MB.; Humphrey, PA.; Srigley, JR.; De Leval, L.; Radhakrishnan, A.; Oliva, E. (Apr 2007). "Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term.". Am J Surg Pathol 31 (4): 489-500. doi:10.1097/PAS.0b013e31802bdd56. PMID 17414095.
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