Difference between revisions of "Cribriform adenocarcinoma of the minor salivary gland"

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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712093/figure/Fig1/  CAMSG (nih.gov)].<ref name=pmid23821209/>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712093/figure/Fig1/  CAMSG (nih.gov)].<ref name=pmid23821209/>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712093/figure/Fig3/ CAMSG (nih.gov)].<ref name=pmid23821209>{{Cite journal  | last1 = Michal | first1 = M. | last2 = Kacerovska | first2 = D. | last3 = Kazakov | first3 = DV. | title = Cribriform adenocarcinoma of the tongue and minor salivary glands: a review. | journal = Head Neck Pathol | volume = 7 Suppl 1 | issue =  | pages = S3-11 | month = Jul | year = 2013 | doi = 10.1007/s12105-013-0457-9 | PMID = 23821209 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712093/figure/Fig3/ CAMSG (nih.gov)].<ref name=pmid23821209>{{Cite journal  | last1 = Michal | first1 = M. | last2 = Kacerovska | first2 = D. | last3 = Kazakov | first3 = DV. | title = Cribriform adenocarcinoma of the tongue and minor salivary glands: a review. | journal = Head Neck Pathol | volume = 7 Suppl 1 | issue =  | pages = S3-11 | month = Jul | year = 2013 | doi = 10.1007/s12105-013-0457-9 | PMID = 23821209 }}</ref>
==IHC==
Features:<ref name=pmid21716087>{{Cite journal  | last1 = Skalova | first1 = A. | last2 = Sima | first2 = R. | last3 = Kaspirkova-Nemcova | first3 = J. | last4 = Simpson | first4 = RH. | last5 = Elmberger | first5 = G. | last6 = Leivo | first6 = I. | last7 = Di Palma | first7 = S. | last8 = Jirasek | first8 = T. | last9 = Gnepp | first9 = DR. | title = Cribriform adenocarcinoma of minor salivary gland origin principally affecting the tongue: characterization of new entity. | journal = Am J Surg Pathol | volume = 35 | issue = 8 | pages = 1168-76 | month = Aug | year = 2011 | doi = 10.1097/PAS.0b013e31821e1f54 | PMID = 21716087 }}</ref>
*AE1/AE3 +ve (12/12 cases).
*CAM5.2 +ve (12/12 cases).
*CK7 +ve (12/12 cases).
*CK8 +ve (12/12 cases).
*CK18 +ve (12/12 cases).
*S-100 +ve (12/12 cases).
*Vimentin +ve (12/12 cases).
*CD117 -ve/+ve (5+ve/12 cases).


==See also==
==See also==

Revision as of 18:31, 18 March 2015

Cribriform adenocarcinoma of the minor salivary gland, abbreviated CAMSG, is a rare malignancy of the salivary gland, typically of the tongue.[1]

It is also known as cribriform adenocarcioma of the tongue, abbreviated CAT.

General

  • Rare.
  • Typically tongue - first described there.[2]
  • Good prognosis[1] - on limited data.

Microscopic

Features:

  • Typically covered by an intact squamous epithelium.[1]
  • Growth patterns - cribriform and solid.
  • Cytology similar to papillary thyroid carcinoma.[1]
    • Irregular (raisin-like) nuclear membranes.
    • Nuclear overlap.

DDx:

Images

www:

IHC

Features:[1]

  • AE1/AE3 +ve (12/12 cases).
  • CAM5.2 +ve (12/12 cases).
  • CK7 +ve (12/12 cases).
  • CK8 +ve (12/12 cases).
  • CK18 +ve (12/12 cases).
  • S-100 +ve (12/12 cases).
  • Vimentin +ve (12/12 cases).
  • CD117 -ve/+ve (5+ve/12 cases).

See also

Referencess

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Skalova, A.; Sima, R.; Kaspirkova-Nemcova, J.; Simpson, RH.; Elmberger, G.; Leivo, I.; Di Palma, S.; Jirasek, T. et al. (Aug 2011). "Cribriform adenocarcinoma of minor salivary gland origin principally affecting the tongue: characterization of new entity.". Am J Surg Pathol 35 (8): 1168-76. doi:10.1097/PAS.0b013e31821e1f54. PMID 21716087.
  2. ↑ Michal, M.; Skálová, A.; Simpson, RH.; Raslan, WF.; Curík, R.; Leivo, I.; Mukensnábl, P. (Dec 1999). "Cribriform adenocarcinoma of the tongue: a hitherto unrecognized type of adenocarcinoma characteristically occurring in the tongue.". Histopathology 35 (6): 495-501. PMID 10583573.
  3. ↑ 3.0 3.1 Michal, M.; Kacerovska, D.; Kazakov, DV. (Jul 2013). "Cribriform adenocarcinoma of the tongue and minor salivary glands: a review.". Head Neck Pathol 7 Suppl 1: S3-11. doi:10.1007/s12105-013-0457-9. PMID 23821209.
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