Connective tissue diseases
Revision as of 02:57, 3 February 2012 by Michael (talk | contribs) (→Osteogenesis imperfecta: more)
Connective tissue diseases are infrequently seen by pathologists.
They may be very important in the context of forensic pathology, as they may be an explanation for multiple fractures
Specific entities
Ehlers-Danlos syndrome
Main article: Ehlers-Danlos syndrome
Marfan syndrome
Main article: Marfan syndrome
Osteogenesis imperfecta
- Abbreviated OI.
General
- Rare.
- Numerous subtypes.
- May be misdiagnosed as child abuse.[1]
General
- Classic - tibial bowing (saber shins).[2]
Microscopic
Features:[2]
- Abundant plump osteoblasts (infants only).
- Paucity of bony matrix.
Images:
See also
References
- ↑ Singh Kocher, M.; Dichtel, L. (Nov 2011). "Osteogenesis imperfecta misdiagnosed as child abuse.". J Pediatr Orthop B 20 (6): 440-3. doi:10.1097/BPB.0b013e328347a2e1. PMID 21716141.
- ↑ 2.0 2.1 Milgram, JW.; Flick, MR.; Engh, CA. (Apr 1973). "Osteogenesis imperfecta. A histopathological case report.". J Bone Joint Surg Am 55 (3): 506-15. PMID 4703203.