Collagenous gastritis

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Collagenous gastritis
Diagnosis in short

LM collagen band in superficial lamina propria
LM DDx amyloidosis of the stomach, signet ring cell carcinoma
Stains trichrome stain - demonstrate collagen
Site stomach

Associated Dx celiac sprue (in adults), collagenous colitis (in adults)
Symptoms +/-dyspepsia
Prevalence extremely rare
Blood work +/-anemia

Collagenous gastritis is an extremely rare pathology of the stomach. It is seen in children and adults.

General

  • Very rare ~ 30 cases reported in total in 2009.[1][2]

Clinical

children:[3]

  • Dyspepsia or anemia.
  • Chronic.

Adults:[1]

Gross

  • Discolored depression - focal.[2]

Microscopic

Features:

  • Band of eosinophilic material (collagen) expands superficial lamina propria.[2]
    • Band of collagen must be as thick as RBC diameter.

DDx:

Images

Stains

See also

References

  1. 1.0 1.1 Brain, O.; Rajaguru, C.; Warren, B.; Booth, J.; Travis, S. (Dec 2009). "Collagenous gastritis: reports and systematic review.". Eur J Gastroenterol Hepatol 21 (12): 1419-24. doi:10.1097/MEG.0b013e32832770fa. PMID 19730387.
  2. 2.0 2.1 2.2 2.3 Jin, X.; Koike, T.; Chiba, T.; Kondo, Y.; Ara, N.; Uno, K.; Asano, N.; Iijima, K. et al. (Sep 2013). "Collagenous gastritis.". Dig Endosc 25 (5): 547-9. doi:10.1111/j.1443-1661.2012.01391.x. PMID 23363075.
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