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Difference between revisions of "Chronic sialadenitis"
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'''Chronic sialadenitis''' is a chronic inflammatory process involving a [[salivary glands|salivary gland]]. | |||
'''Chronic sailolithiasis''' redirects here. '''Sialadenitis''' redirects here. | |||
'''Chronic sclerosing sialadenitis''' (also known as '''Küttner tumour'''<ref name=pmid32754389>{{cite journal |authors=Keidar E, Shermetaro J, Kwartowitz G |title=Pediatric Parotid Chronic Sclerosing Sialadenitis in an African-American Female: A Rare Case and Review of the Literature |journal=Cureus |volume=12 |issue=6 |pages=e8846 |date=June 2020 |pmid=32754389 |pmc=7386075 |doi=10.7759/cureus.8846 |url=}}</ref>) redirects here. | |||
==General== | |||
*Occasionally associated with malignancy, e.g. [[adenoid cystic carcinoma]].<ref name=pmid21159490>{{cite journal |author=Hasegawa M, Cheng J, Maruyama S, ''et al.'' |title=Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background |journal=Int J Oral Maxillofac Surg |volume=40 |issue=6 |pages=647–50 |year=2011 |month=June |pmid=21159490 |doi=10.1016/j.ijom.2010.11.009 |url=}}</ref> | |||
Etiology:<ref>URL: [http://emedicine.medscape.com/article/882358-overview http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview]. Accessed on: 10 January 2011.</ref> | |||
*Infection. | |||
*Autoimmune (e.g. [[Sjögren syndrome]], [[systemic lupus erythematosus]]). | |||
*Other. | |||
Associations: | |||
*[[Smoking]].<ref name=pmid2037973>{{cite journal |author=Eliasson L, Heyden G, Landahl S, Steen B |title=Effects of tobacco and diuretics on human palatal salivary glands |journal=J. Oral Pathol. Med. |volume=20 |issue=3 |pages=126–9 |year=1991 |month=March |pmid=2037973 |doi= |url=}}</ref> (???) | |||
==Gross== | |||
Features: | |||
*Typical location: submandibular salivary gland. | |||
*Salivary gland swelling.<ref name=pmid21159490/> | |||
==Microscopic== | |||
Features: | |||
*Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, [[plasma cell]]s). | |||
*Fibrosis. | |||
*+/-Calcifications. | |||
Note: | |||
*If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a ''[[Focus score]]'' should be considered. | |||
DDx: | |||
*[[Lymphoma]] - especially [[MALT lymphoma]].<ref name=pmid22475637>{{Cite journal | last1 = Beasley | first1 = MJ. | title = Lymphoma of the Thyroid and Head and Neck. | journal = Clin Oncol (R Coll Radiol) | volume = | issue = | pages = | month = Apr | year = 2012 | doi = 10.1016/j.clon.2012.02.010 | PMID = 22475637 }}</ref> | |||
*[[IgG4-related systemic diseases|IgG4-related sialadenitis]].<ref name=pmid31760789>{{cite journal |authors=Thompson LDR |title=IgG4-Related Sialadenitis |journal=Ear Nose Throat J |volume= |issue= |pages=145561319890153 |date=November 2019 |pmid=31760789 |doi=10.1177/0145561319890153 |url=}}</ref> | |||
===Image=== | |||
<gallery> | |||
Image:Chronic_sialadenitis.jpg | Chronic sialadenitis. (WC/Nephron) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
SUBMANDIBULAR GLAND, RIGHT, EXCISION: | |||
- CHRONIC SIALOADENITIS. | |||
- SIALOLITHIASIS. | |||
- TWO BENIGN LYMPH NODES. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
====Micro==== | |||
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell | |||
infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. | |||
Significant nuclear atypia is not identified. | |||
=====Alternate===== | |||
The sections show a salivary gland with a patchy mixed mononuclear cell infiltrate and fibrosis. Significant nuclear atypia is not identified. Plasma cells are not prominent. Germinal centres are present. | |||
==See also== | |||
*[[Salivary gland]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Salivary gland]] | |||