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Difference between revisions of "Case 85"
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→Diagnosis
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[Papillary cystadenoma of the epididymis]]</center><br> | {{hidden|Diagnosis|<center>[[Papillary cystadenoma of the epididymis]]</center><br> | ||
Comment:<br>This may occur in [[von Hippel-Lindau disease]]. In the context of von Hippel-Lindau disease, it is usually bilateral and the patient is younger.}} | Comment:<br>This may occur in [[von Hippel-Lindau disease]]. In the context of von Hippel-Lindau disease, it is usually bilateral and the patient is younger. | ||
The main (morphologic) differential diagnosis is [[clear cell renal cell carcinoma]]. | |||
The immunoprofile of this lesion is like [[clear cell tubulopapillary renal cell carcinoma]] (also known as ''clear cell papillary RCC''); it is CK7 positive, CD10 negative, AMACR negative, PAX8 positive.<ref name=pmid24441657>{{Cite journal | last1 = Cox | first1 = R. | last2 = Vang | first2 = R. | last3 = Epstein | first3 = JI. | title = Papillary cystadenoma of the epididymis and broad ligament: morphologic and immunohistochemical overlap with clear cell papillary renal cell carcinoma. | journal = Am J Surg Pathol | volume = 38 | issue = 5 | pages = 713-8 | month = May | year = 2014 | doi = 10.1097/PAS.0000000000000152 | PMID = 24441657 }}</ref> One should check if there is a kidney mass. | |||
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