Difference between revisions of "Cartilage"

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It comes in three flavours:<ref name=Ref_WFH4_173-5>{{Ref WFH4|173-5}}</ref><ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Cartilage/Cartil.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Cartilage/Cartil.htm]. Accessed on: 2 January 2011.</ref>
It comes in three flavours:<ref name=Ref_WFH4_173-5>{{Ref WFH4|173-5}}</ref><ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Cartilage/Cartil.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Cartilage/Cartil.htm]. Accessed on: 2 January 2011.</ref>
#Hyaline cartilage, e.g. trachea.
#Hyaline cartilage, e.g. [[trachea]].
#Fibrocartilage, e.g. intervertebral disc.
#Fibrocartilage, e.g. intervertebral disc.
#Elastic cartilage, e.g. epiglottis.
#Elastic cartilage, e.g. epiglottis.
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*Round cells.  
*Round cells.  


==Hyaline cartilage==
==Differential diagnosis==
Cartilage - general for the site:<ref name=pmid17031677>{{Cite journal  | last1 = Krenn | first1 = V. | last2 = Morawietz | first2 = L. | last3 = König | first3 = A. | last4 = Haeupl | first4 = T. | title = [Differential diagnosis of chronic synovitis]. | journal = Pathologe | volume = 27 | issue = 6 | pages = 402-8 | month = Nov | year = 2006 | doi = 10.1007/s00292-006-0866-6 | PMID = 17031677 }}</ref>
*[[Synovial chondromatosis]].
*[[Gout]].
*[[Pseudogout]].
*[[Storage disorders]].
*[[Granuloma|Granulomatous inflammation]].
*Degenerative changes ([[osteoarthritis]]).
*[[Rheumatic joint disease|Rheumatic disease]].
*[[Diffuse tenosynovial giant-cell tumour]].
 
==Normal==
===Hyaline cartilage===
====Microscopic====
Features:<ref name=Ref_EH2_178>{{Ref EH2|178}}</ref>
Features:<ref name=Ref_EH2_178>{{Ref EH2|178}}</ref>
*Chondrocytes within small pockets (lacunae) of extracellular matrix.
*Chondrocytes within small pockets (lacunae) of extracellular matrix.
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Image:
Image:
*[http://en.wikipedia.org/wiki/File:Cartilage_polarised.jpg Hyaline cartilage - polarised (WC)].
<gallery>
Image:Cartilage polarised.jpg | Hyaline cartilage - polarized. (WC)
</gallery>
 
===Perichondrium===
====Microscopic====
Features:
*Around cartilage.
**Increased cellular density.
**Spindle cells with poorly defined cellular borders in an eosinophilic (fibrous) stroma.
 
Images:
*[http://apbrwww5.apsu.edu/thompsonj/Anatomy%20&%20Physiology/2010/2010%20Exam%20Reviews/Exam%201%20Review/perichondrium.jpg Perichondrium (apsu.edu)].<ref>URL: [http://apbrwww5.apsu.edu/thompsonj/Anatomy%20&%20Physiology/2010/2010%20Exam%20Reviews/Exam%201%20Review/Ch04%20Mineralized%20Connective%20Tissues.htm http://apbrwww5.apsu.edu/thompsonj/Anatomy%20&%20Physiology/2010/2010%20Exam%20Reviews/Exam%201%20Review/Ch04%20Mineralized%20Connective%20Tissues.htm]. Accessed on: 19 September 2012.</ref>
*[http://apbrwww5.apsu.edu/thompsonj/Anatomy%20&%20Physiology/2010/2010%20Exam%20Reviews/Exam%201%20Review/perichondrium02.gif Perichondrium (apsu.edu)].


=Tumours=
=Tumours=
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==Synovial chondromatosis==
==Synovial chondromatosis==
*[[AKA]] ''synovial osteochondromatosis''.
*[[AKA]] ''synovial osteochondromatosis''.
===General===
{{Main|Synovial chondromatosis}}
*Benign.
**Malignant transformation rare <5%.<ref name=pmid17848703/>
*Classically location: knee.<ref name=pmid17848703>{{Cite journal  | last1 = Murphey | first1 = MD. | last2 = Vidal | first2 = JA. | last3 = Fanburg-Smith | first3 = JC. | last4 = Gajewski | first4 = DA. | title = Imaging of synovial chondromatosis with radiologic-pathologic correlation. | journal = Radiographics | volume = 27 | issue = 5 | pages = 1465-88 | month =  | year =  | doi = 10.1148/rg.275075116 | PMID = 17848703 | URL = http://radiographics.rsna.org/content/27/5/1465.long }}</ref>
 
===Radiology===
*Intraarticular calcifications.
 
===Microscopic===
Features:<ref name=pmid17848703/>
*Hyaline cartilage +/- lobular surface.
**May have lacunae with binucleate cells.
*+/-Synovial hyperplasia - ribbon like tissue with an epithelium that has eosinophilic cytoplasm.
*Bone.
 
Images:
*[http://radiographics.rsna.org/content/27/5/1465.long Synovial chondromatosis (rsna.org)].
*[http://radiographics.rsna.org/content/27/5/1465.long Synovial chondromatosis - high mag. (rsna.org)].
*[http://www.webpathology.com/image.asp?n=1&Case=369 Synovial chondromatosis (webpathology.com)].
 
*[[Chondrosarcoma]].
 


=See also=
=See also=
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*[[Bone]].
*[[Bone]].
*[[Spine]].
*[[Spine]].
*[[Joints]].


==References==
==References==
48,436

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