Difference between revisions of "Cartilage"
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#Elastic cartilage, e.g. epiglottis. | #Elastic cartilage, e.g. epiglottis. | ||
=General= | |||
Features of cartilage:<ref name=Ref_EH2_178-9>{{Ref EH2|178-9}}</ref> | Features of cartilage:<ref name=Ref_EH2_178-9>{{Ref EH2|178-9}}</ref> | ||
*Avascular. | *Avascular. | ||
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*[http://en.wikipedia.org/wiki/File:Cartilage_polarised.jpg Hyaline cartilage - polarised (WC)]. | *[http://en.wikipedia.org/wiki/File:Cartilage_polarised.jpg Hyaline cartilage - polarised (WC)]. | ||
=Tumours= | |||
{{Main|Chondro-osseous tumours}} | {{Main|Chondro-osseous tumours}} | ||
Tumours of cartilage are dealt with in the article ''[[chondro-osseous tumours]]'' together with bone tumours. | Tumours of cartilage are dealt with in the article ''[[chondro-osseous tumours]]'' together with bone tumours. | ||
==See also | =Specific diagnoses= | ||
==Synovial chondromatosis== | |||
*[[AKA]] ''synovial osteochondromatosis''. | |||
===General=== | |||
*Benign. | |||
**Malignant transformation rare <5%.<ref name=pmid17848703/> | |||
*Classically location: knee.<ref name=pmid17848703>{{Cite journal | last1 = Murphey | first1 = MD. | last2 = Vidal | first2 = JA. | last3 = Fanburg-Smith | first3 = JC. | last4 = Gajewski | first4 = DA. | title = Imaging of synovial chondromatosis with radiologic-pathologic correlation. | journal = Radiographics | volume = 27 | issue = 5 | pages = 1465-88 | month = | year = | doi = 10.1148/rg.275075116 | PMID = 17848703 | URL = http://radiographics.rsna.org/content/27/5/1465.long }}</ref> | |||
===Radiology=== | |||
*Intraarticular calcifications. | |||
===Microscopic=== | |||
Features:<ref name=pmid17848703/> | |||
*Hyaline cartilage +/- lobular surface. | |||
**May have lacunae with binucleate cells. | |||
*+/-Synovial hyperplasia - ribbon like tissue with an epithelium that has eosinophilic cytoplasm. | |||
*Bone. | |||
Images: | |||
*[http://radiographics.rsna.org/content/27/5/1465.long Synovial chondromatosis (rsna.org)]. | |||
*[http://radiographics.rsna.org/content/27/5/1465.long Synovial chondromatosis - high mag. (rsna.org)]. | |||
*[http://www.webpathology.com/image.asp?n=1&Case=369 Synovial chondromatosis (webpathology.com)]. | |||
*[[Chondrosarcoma]]. | |||
=See also= | |||
*[[Chondro-osseous tumours]]. | *[[Chondro-osseous tumours]]. | ||
*[[Bone]]. | *[[Bone]]. | ||
Revision as of 14:17, 9 February 2012
Cartilage is a type of connective tissue that does not commonly come across the pathologist's desk.
It comes in three flavours:[1][2]
- Hyaline cartilage, e.g. trachea.
- Fibrocartilage, e.g. intervertebral disc.
- Elastic cartilage, e.g. epiglottis.
General
Features of cartilage:[3]
- Avascular.
- Extracellular matrix with bluish tinge.
- Round cells.
Hyaline cartilage
Features:[4]
- Chondrocytes within small pockets (lacunae) of extracellular matrix.
- Chondrocytes:
- Spherical nucleus.
- Prominent nucleolus.
- Clear cytoplasm.
- Extracellular matrix:
- Blue-white appearance on H&E stain -- key feature.
- Chondrocytes:
Image:
Tumours
Main article: Chondro-osseous tumours
Tumours of cartilage are dealt with in the article chondro-osseous tumours together with bone tumours.
Specific diagnoses
Synovial chondromatosis
- AKA synovial osteochondromatosis.
General
Radiology
- Intraarticular calcifications.
Microscopic
Features:[5]
- Hyaline cartilage +/- lobular surface.
- May have lacunae with binucleate cells.
- +/-Synovial hyperplasia - ribbon like tissue with an epithelium that has eosinophilic cytoplasm.
- Bone.
Images:
- Synovial chondromatosis (rsna.org).
- Synovial chondromatosis - high mag. (rsna.org).
- Synovial chondromatosis (webpathology.com).
See also
References
- ↑ Young, Barbara; Lowe, James S.; Stevens, Alan; Heath, John W.; Deakin, Philip J. (2000). Wheaters Functional Histology (4th ed.). Churchill Livingstone. pp. 173-5. ISBN 978-0004881973.
- ↑ URL: http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Cartilage/Cartil.htm. Accessed on: 2 January 2011.
- ↑ Cormack, David H. (2001). Essential Histology (2nd ed.). Lippincott Williams & Wilkins. pp. 178-9. ISBN 978-0781716680.
- ↑ Cormack, David H. (2001). Essential Histology (2nd ed.). Lippincott Williams & Wilkins. pp. 178. ISBN 978-0781716680.
- ↑ 5.0 5.1 5.2 Murphey, MD.; Vidal, JA.; Fanburg-Smith, JC.; Gajewski, DA.. "Imaging of synovial chondromatosis with radiologic-pathologic correlation.". Radiographics 27 (5): 1465-88. doi:10.1148/rg.275075116. PMID 17848703.